UTHSCSA Faculty Profiles v1.0

Szabo, Charles Akos

School of Medicine
(210) 450-0500

Since my arrival to San Antonio over twenty years ago, my main goal was to develop the South Texas Comprehensive Epilepsy Center (STCEC) into a leading epilepsy program in Texas. The STCEC represents a unique collaboration between the UT Health San Antonio, the University Health System (UHS) and the Audie Murphy Veterans Administration Hospital. The program grew from two epilepsy faculty in 1996 to seven members in 2017, providing excellent state-of-the-art epilepsy care at each of these facilities, including an epilepsy surgery program at UHS, treating adults and children. Our group includes two neurosurgeons, two neuropsychologists and several nurses. We have accredited as Level 4 Epilepsy Program by the National Association of Epilepsy Centers for over 10 years, and the only one in South Texas. I have continued my administrative engagement as the Chief of Epilepsy, Co-Director of the STCEC and Director of the Epilepsy Surgery Program. I also fostered close collaboration with the Epilepsy Foundation of Central and South Texas, with our faculty serving clinics in the Rio Grande Valley (Harlingen, Laredo, Eagle Pass, and Del Rio).
Aside from my clinical and administrative activities in Epilepsy, I was the director of the Clinical Neurophysiology Fellowship program in 2000-2005, and from December 2007 to May 2009, I served as the Interim Chair of the newly formed Department of Neurology. This period was challenging in that clinical and administrative infrastructure needed for the fledgling department, while continuing unabated support for the existing research and academic missions.
My research activities have been in part clinical, ranging from participation in pharmaceutical studies to case reports and manuscripts on neurobehavioral effects and neuroimaging in epilepsy. My main focus was characterization of a natural model of genetic generalized epilepsy in a baboon colony housed at the Texas Biomedical Research Institute. As my ultimate goal is to develop an important resource to study mechanisms of epilepsy and sudden unexpected death in epilepsy and evaluate interventions and preclinical therapies, I have pursued epidemiological, electroclinical and neuroimaging studies in epileptic baboons, developing a neuroimaging and electrophysiological platforms to study this model. This has resulted in several NIH-funded and commercial grants, some evaluating the mechanisms underlying epilepsy in the baboon using functional positron emission tomography and/or structural and functional MRI, invasive EEG, and histopathology with immunohistochemistry, while others studied the efficacy of antiepileptic medications and neurostimulation, including vagal nerve stimulation and responsive (intracranial) neurostimulation, in epileptic baboons. My newest aim is to characterize epileptogenesis in order to develop antiepileptogenic interventions.

1/2016 - Present Adjunct Scientist Texas Biomedical Research Institute, San Antonio, TX
1/2014 - Present CME Director Southern Epilepsy and EEG Society
9/2010 - Present Professor UTHSCSA, Neurology, San Antonio, TX
6/2009 - Present Chief of Epilepsy UTHSCSA, Neurology, San Antonio, TX
9/2005 - Present Co-Director of the South Texas Comprehensive Epilepsy Center UTHSCSA/UHS/AMVAH, Neurology, San Antonio, TX
9/2003 - Present Director of Epilepsy Surgery Program University Health System, San Antonio, TX