UTHSCSA Faculty Profiles v1.0

Kudolo, George B

School of Health Professions
Clinical Laboratory Sciences
(210) 567-4316

My primary responsibility is teaching clinical chemistry and research courses in the undergraduate Clinical Laboratory Sciences program, laboratory medicine to the students in the Masters in Physician Assistant Studies and the advisor and sole instructor in toxicology, and director of the Graduate Toxicology Program.

In the Clinical Laboratory Sciences, I emphasize how accurately clinical chemistry tests (specimen choice, quality and the role of interferences) must be performed to help the physician make diagnosis, monitor and treatment of diseases. In the Physician Assistant Program the emphasis is on the interpretation of the results from the laboratory and who to contact for further help in requesting appropriate tests and how to reduce duplicate and unnecessary tests. In the Graduate Toxicology program, which specializes in postmortem Forensic Toxicology, the emphasis shifts to when things go wrong and the fatality from properly or improperly prescribed drugs. Here the emphasis is on the measurement of drugs in body fluids in the living and the dead to help the medical examiner determine the cause of death, manner of death and the mechanism of death.
The following three objectives form the pillars that drive teaching philosophies across the three programs: (1). Establish a unique and the best Graduate Toxicology Program in Texas, (2). Help students fulfill their expectations and develop their full potential, and (3). Produce highly educated well-rounded laboratory and healthcare workers.

As a research scientist I have lived and worked on three continents, have conducted research in nutrition, diabetes, reproduction and Complementary and Alternative Medicine (CAM). I believe my research experience helps me to teach effectively in my clinical chemistry and toxicology courses. I consider myself a very versatile scientist, who has worked with animal models, from rats to non-human primates (Vervet and Sykes monkeys and baboons), and performed research on organ systems ranging from the female reproductive tract (ovaries and uterus and blastocysts) to the kidney and studied compounds from steroids to prostanoids. I have special interest in cardiovascular disease studying hypercholesterolemia and platelet function. I have conducted human clinical trials with orthodox medications (statins and hypoglycemic agents) as well as the herbal supplement Ginkgo biloba extract. My current interests are the effect of herbal remedies on clinical laboratory tests and postmenopausal symptoms, drug-herb interactions and toxicity, and soy phytoestrogens. I was first scientist to demonstrate that the ingestion of Ginkgo biloba extract induces an increase in beta cell pancreatic insulin production. I believe that the connection between Ginkgo biloba ingestion and memory enhancement is linked to increased brain insulin levels. I believe my studies in Ginkgo biloba extract may help to explain the drive to classify Alzheimers disease as Type III diabetes.
I have been a consultant (as part of my clinical practice) by local attorneys on legal cases involving postmortem toxicology and blood alcohols in fatal drunk driving.

My research activity has diminished because of my teaching load, as for the past 20 years, and single-handedly, I have had to develop the Graduate Toxicology Program from the ground up and be the only instructor in the program. This is a specialized program and trains only a handful of toxicologists a year but it is a very important area that must be supported.

9/2008 - Present Adjunct Professor, School of Public Health, San Antonio Regional campus University of Texas School of Public Health, San Antonio Regional campus, San Antonio, TX
9/2005 - Present Full Professor with tenure and Graduate Toxicology Program Director University of Texas HSC, Clinical Laboratory Sciences, San Antonio, TX