Journal Article |
| Kannan TR, Coalson JJ, Cagle M, Musatovova O, Hardy RD, Baseman JB. Synthesis and Distribution of CARDS Toxin During Mycoplasma pneumoniae Infection in a Murine Model J Infect Dis 2011 Sep;204:1596-1604.
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| Zhang W, Baseman JB. Transcriptional regulation of MG_149, an osmoinducible lipoprotein gene from Mycoplasma genitalium Mol Microbiol 2011 Jul;81(2):327-339.
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| Tagliabue C, C Techasaensiri, JP Torres, K Katz, C Meek, TR Kannan, JJ Coalson, S Esposito, N Principi, R Leff, JB Baseman, RD Hardy. Efficacy of increasing dosages of clarithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia J Antimicrob Chemother 2011 Jul;66(10):2323-2329.
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| Johnson C, Kannan TR, Baseman JB. Cellular Vacuoles Induced by Mycoplasma pneumoniae CARDS Toxin Originate from Rab9-Associated Compartments PLoS One 2011 Jul;6(7):22877-22877.
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| Peters J, Singh H, Brooks EG, Diaz J, Kannan TR, Coalson JJ, Baseman JG, Cagle M, Baseman JB. Persistence of CARDS Toxin-producing Mycoplasma pneumoniae in Refractory Asthma Chest 2011 May;140:401-407.
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| Zhang W, Baseman JB. Transcriptional response of Mycoplasma genitalium to osmotic stress Microbiology 2011 Feb;157:548-556.
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| Kannan, T.R., R.D. Hardy, J.J. Coalson, D.C. Cavuoti, J.D. Siegel, M. Cagle, O. Musatovova, C. Herrera and Baseman JB. Fatal outcomes in family transmission of Mycoplasma pneumoniae (in press) Clin. Infect. Dis 2011 Jan;.
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| Muir MT, SM Cohn, C Louden, TR Kannan, JB Baseman. Novel toxin assays implicate Mycoplasma pneumoniae in prolonged ventilator course and hypoxemia Chest 2011 Jan;139:305-310.
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| Somarajan SR, Kannan TR, Baseman JB. Mycoplasma pneumoniae Mpn133 is a cytotoxic nuclease with a glutamic acid-, lysine- and serine-rich region essential for binding and internalization but not enzymatic activity Cell Microbiol 2010 Aug;12(12):1821-1831.
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| Kannan TR, Musatovova O, Balasubramanian S, Cagle M, Jordan JL, Krunkosky TM, Davis A, Hardy RD, Baseman JB. Mycoplasma pneumoniae Community Acquired Respiratory Distress Syndrome toxin expression reveals growth phase and infection-dependent regulation Mol Microbiol 2010 Jun;76(5):1127-1141.
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| Pakhamova, ON, AB Taylor, A Becker, SP Holloway, TR Kannan, JB Baseman and PJ Hart. Crystallization of community acquired respiratory distress syndrome toxin from Mycoplasma pneumoniae Acta Cryst 2010 Jan;F66:294-296.
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| Li, L, M. Krishnan, JB Baseman. Molecular cloning, expression and characterization of a Ca2 dependent, membrane associated nuclease of Mycoplasma genitalium J Bact 2010 Jan;192:4876-4884.
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| Techasaensiri C, C Tagliabue, M Cagle, P Iranpour, K Katz, TR Kannan, JJ Coalson, JB Baseman and RD Hardy. Variation in colonization, ADP-ribosylating cytotoxin,and pulmonary disease severity among Mycoplasma pneumoniae strains Am J Res Crit Care Med 2010 Jan;182:797-804.
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| Saikolappan S, Sasindran SJ, Yu HD, Baseman JB, Dhandayuthapani S. The Mycoplasma genitalium MG_454 gene product resists killing by organic hydroperoxides J Bacteriol 2009 Nov;191(21):6675-6682.
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| Johnson C, Kannan TR, Baseman JB. Characterization of a unique ADP-ribosyltransferase of Mycoplasma penetrans Infect Immun 2009 Oct;77(10):4362-4370.
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| Hardy, RD, Coalson JJ, Peters, JI, Chaparro, A, Techasaensiri, C, Cantwell AM, Kannan TR, Baseman JB, Dube PH. Analysis of Pulmonary Inflammation and Function in the Mouse and Baboon after Exposure to Mycoplasma pneumoniae CARDS Toxin Public Library of Science (PLoS ONE) 2009 Oct;4(10).
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| Berg CP, Kannan TR, Klein R, Gregor M, Baseman JB, Wesselborg S, Lauber K, Stein GM. Mycoplasma antigens as a possible trigger for the induction of antimitochondrial antibodies in primary biliary cirrhosis Liver Int 2009 Jul;29(6):797-809.
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| Musatovova O, Baseman JB. Analysis identifying common and distinct sequences among Texas clinical strains of Mycoplasma genitalium J Clin Microbiol 2009 May;47(5):1469-1475.
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| Wang J, Chen L, Chen F, Zhang X, Zhang Y, Baseman J, Perdue S, Yeh IT, Shain R, Holland M, Bailey R, Mabey D, Yu P, Zhong G. A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice Vaccine 2009 May;27(22):2967-2980.
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| Thurman, AR; Musatovova, O; Perdue, S; Shain RN; Baseman, JB. Mycoplasma genitalium symptoms, concordance and treatment in high-risk sexual dyads Int J STD AIDS 2009 Jan;21:177-183.
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| Kannan TR, Musatovova O, Gowda P, Baseman JB. Characterization of a unique ClpB protein of Mycoplasma pneumoniae and its impact on growth Infect Immun 2008 Sep;76(11):5082-5092.
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| Balasubramanian S, Kannan TR, Baseman JB. Surface-exposed carboxyl region of Mycoplasma pneumoniae elongation factor-Tu interacts with fibronectin Infect Immun 2008 Apr;76(7):3116-3123.
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| Ueno PM, Timenetsky J, Centonze VE, Wewer JJ, Cagle M, Stein MA, Krishnan M, Baseman JB. Interaction of Mycoplasma genitalium with host cells: evidence for nuclear localization Microbiology 2008 Jan;54:3033-3041.
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| Musatovova O, Kannan TR, Baseman JB. Genomic analysis reveals Mycoplasma pneumoniae repetitive element 1-mediated recombination in a clinical isolate Infect Immun 2008 Jan;76(4):1639-1648.
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Book Chapter |
| Baseman JB and K. Waites. Mycoplasma: Curiosity and Pathogen. In: N. Cary Engleberg, Victor DiRita, Terence S. Dermody. Schaechters Mechanisms of Microbial Disease, 5th Edition. 2010. |
Federal |
| Funding Agency |
National Institutes of Health |
| Title |
Role of unique ADP-ribosylating vacuolating Mycoplasma pneumoniae toxin in asthma |
| Status |
Active |
| Period |
8/2011 - 7/2016 |
| Role |
Principal Investigator |
| Grant Detail |
The San Antonio Asthma and Allergic Diseases Cooperative Research Center represents an integrative, collaborative and innovative multidisciplinary effort to investigate the role of a unique Mycoplasma pneumoniae toxin in asthma and related airway diseases. |
| Funding Agency |
NIH |
| Title |
Molecular Mechanisms of Microbial Pathogenesis |
| Status |
Active |
| Period |
9/2009 - 8/2014 |
| Role |
Co-Investigator |
| Grant Detail |
|
| Funding Agency |
Department of Defense |
| Title |
A Civilian Military Trauma Institute |
| Status |
Active |
| Period |
4/2010 - 9/2012 |
| Role |
Principal Investigator |
| Grant Detail |
|
| Funding Agency |
HRSA |
| Title |
Research Focused Initiative |
| Status |
Active |
| Period |
9/2010 - 8/2012 |
| Role |
Principal Investigator |
| Grant Detail |
|
| Funding Agency |
National Institute of Allergy and Infectious Disease (NIH) |
| Title |
Role of Unique ADP Ribosylating Vacuolating Mycoplasma pneumoniae Toxin in Asthma - American Recovery and Reinvestment Act (ARRA) Administrative Supplemental Award, Mycoplasma pneumoniae Infection in a Pediatric Population |
| Status |
Complete |
| Period |
9/2009 - 8/2011 |
| Role |
Principal Investigator |
| Grant Detail |
This study is a comparison of rates of infection with Mycoplasma pneumoniae in 3 groups of pediatric subjects (acute exacerbation of asthma; outpatient refractory asthma; healthy controls) and of the impact of M.pneumoniae infection on asthma symptoms and quality of life. |
| Funding Agency |
NIH/NIAID |
| Title |
Control of Candida albicans Filamentous Growth and Virulence |
| Status |
Active |
| Period |
9/2009 - 8/2010 |
| Role |
Consultant |
| Grant Detail |
The major goal of this grant is to determine how two key transcriptional regulators function together to control C. albicans filamentous growth. |
Private |
| Funding Agency |
|
| Title |
Robert and Lorrain Bratton Family Trust Prevention of Transmissible Diseases |
| Status |
Active |
| Period |
1/2006 - Present |
| Role |
Co-Investigator |
| Grant Detail |
|
| Funding Agency |
Fein |
| Title |
Bernard and Vera Fein Endowment |
| Status |
Active |
| Period |
11/2010 - Present |
| Role |
Principal Investigator |
| Grant Detail |
To support the development of new strategies and reduce airway disease in infants, children and adults. |
| Funding Agency |
Kleberg Foundation |
| Title |
Chronic Airway Disease - Building upon research excellence for a cure |
| Status |
Active |
| Period |
1/2008 - 12/2013 |
| Role |
Principal Investigator |
| Grant Detail |
Proposal to study the Mycoplasma pneumoniae toxin and its impact on acute and chronic airway diseases and extrapulmonary pathologies in South Texas and beyond. The Community Acquired Respiratory Distress Syndrome Toxin (CARDS TX) is a most unique protein, and we are continually uncovering new and unexpected biological and chemical properties about the CARDS TX that distinguish it from all other known bacterial toxins. Although the CARDS TX bears some similarity to pertussis, diphtheria and helicobacter toxins, it is actually so unusual that it truly needs to be categorized separately. |
