Journal Article |
| Das F, Ghosh-Choudhury N, Dey N, Bera A, Mariappan MM, Kasinath BS, Ghosh-Choudhury G. High Glucose Forces a Positive Feed Back Loop Connecting Akt Kinase and FoxO1 to Activate mTORC1 for Mesangial Cell Hypertrophy and Matrix Protein Expression. PMID: 25288788 [PubMed - as supplied by publisher] J Biol Chem 2014 Oct;.
|
| Das F, Bera A, Ghosh-Choudhury N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression. PMID: 25333702 [PubMed - in proess] PLOS One 2014 Oct;9(10).
|
| Bera A, Das F, Ghosh-Choudhury N, Kasinath BS, Abboud HE, Ghosh-Choudhury G. microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion Exp Cell Res, In Press 2014 Oct;328(1):99-117.
|
| Bera A, Das F, Ghosh-Choudhury N, Li X, Pal S, Gorin Y, Kasinath BS, Abboud HE, Ghosh-Choudhury G. A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF Am J Physiol Cell Physiol 2014 Jun;306(11):C1089-C1100.
|
| Bera, Ghosh-Choudhury N, Dey N, Das F, Kasinath BS, Abboud HE, Choudhury GG. NFkB-Mediated Cyclin D1 Expression By microRNA-21 Influences Renal Cancer Cell Proliferation Cell Signal 2013 Dec;25(12):2575-2586.
|
| Ghosh-Choudhury N, Mandal CC, Das F, Ganapathy S, Ahuja SS, Ghosh-Choudhury G. c-Abl-dependent molecular circuitry involving Smad5 and phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2-induced osteogenesis J Biol Chem 2013 Aug;288(34):24503-24517.
|
| Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Choudhury GG. TGF-induced PI 3 kinase-dependent MNK-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy J Cell Physiol [Epub ahead of print] 2013 Jan;.
|
| Das F, Ghosh-Choudhury N, Bera A, Dey N, Abboud HE, Kasinath BS, Ghosh Choudhury G. TGF integrates SMAD 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy J Biol Chem 2013 Jan;288(11):7756-7768.
|
| Dey N, Ghosh-Choudhury N, Kasinath BS, Choudhury GG. TGF-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion PLoS One 2012 Aug;7(8).
|
| Das F, Ghosh-Choudhury N, Dey N, Mandal CC, Mahimainathan L, Kasinath BS, Abboud HE, Choudhury GG. Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase J Biol Chem 2012 Feb;287(6):3808-22.
|
| Dey N, Das F, Ghosh-Choudhury N, Mandal CC, Parekh DJ, Block K, Kasinath BS, Abboud HE, Choudhury GG. microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion PLoS One 2012 Jan;7(6).
|
| Das F, Dey N, Venkatesan B, Kasinath BS, Ghosh-Choudhury N, Ghosh-Choudhury G. High glucose upregulation of early-onset Parkinsons disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy Cell Signal 2011 Aug;23(8):1311-1319.
|
| Dey N, Das F, Mariappan MM, Mandal CC, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes J Biol Chem 2011 Jul;286(29):25586-25603.
|
| Mandal CC, Ghosh-Choudhury N, Yoneda T, Choudhury GG, Ghosh-Choudhury N. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44 J Biol Chem 2011 Jan;.
|
| Mandal CC, Ghosh-Choudhury N, Yoneda T, Choudhury GG, Ghosh-Choudhury N. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44 J Biol Chem 2011 Jan;.
|
| Mandal CC, Ghosh-Choudhury N, Yoneda T, Choudhury GG, Ghosh-Choudhury N. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44 J Biol Chem 2011 Jan;.
|
| Mandal CC, Drissi H, Ghosh-Choudhury G, Ghosh-Choudhury N. Integration of phosphatidylinositol 3-kinase, Akt kinase, and Smad signaling pathway in BMP-2-induced osterix expression Calcif Tissue Int 2010 Dec;87(6):533-540.
|
| Mandal CC, Ghosh-Choudhury T, Yoneda T, Ghosh-Choudhury G, Ghosh-Choudhury N. Fish oil prevents breast cancer cell metastasis to bone Biochem Biophys Res Commun 2010 Nov;402(4):602-607.
|
| Das F, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. TGF enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy FEBS Lett 2010 Oct;584(19):4268-4272.
|
| Dey N, Ghosh-Choudhury N, Das F, Li X, Venkatesan BA, Barnes JL, Kasinath BS, Ghosh-Choudhury G. PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy J Cell Physiol 2010 Oct;225(1):27-41.
|
| Ghosh-Choudhury N, Mandal CC, Ghosh-Choudhury G. Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth Cell Signal 2010 Jan;22(5):749-758.
|
| Ghosh-Choudhury T, Mandal C, Woodruff K, St Clair P, Fernandes G, Ghosh-Choudhury G, Ghosh-Choudhury N. Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth Breast Cancer Res Treat 2009 Nov;118(1):213-228.
|
| Mandal CC, Ghosh-Choudhury G, Ghosh-Choudhury N. Phosphatidylinositol 3 kinase/Akt signal relay cooperates with smad in bone morphogenetic protein-2-induced colony stimulating factor-1 (CSF-1) expression and osteoclast differentiation Endocrinology 2009 Nov;150(11):4989-4998.
|
| Mahimainathan L, Ghosh-Choudhury N, Venkatesan B, Das F, Mandal CC, Dey N, Habib SL, Kasinath BS, Abboud HE, Ghosh-Choudhury G. TSC2 deficiency increases PTEN via HIF1alpha J Biol Chem 2009 Oct;284(41):2790-2798.
|
Abstract |
| Ghosh-Choudhury N. Reactive Oxygen Species in Bone: A Friend or a Foe; 2011 Jan. (International Conference; vol. S16, no. 208).
|
| Mandal CC, Ghosh-Choudhury N, Yoneda T, Choudhury GG, Ghosh-Choudhury N. Simvastatin Prevents Breast Cancer Skeletal Metastasis by Increasing p53 Levels To Increase PTEN and Inhibit CD44 Expression; 2010 Dec. (Cancer Research; vol. 70, no. 24).
|
| Mandal C, Ghosh-Choudhury N, Yoneda T, Ghosh-Choudhury G, Ghosh-Choudhury N. Unveiling Dual Functions of p53 in Preventing Breast Cancer Bone Metastasis by Simvastatin Targeting CD44 and PTEN; 2010 Oct. (Journal of Bone and Mineral Research; vol. 25, no. 1230).
|
| Ghosh-Choudhury N. Nox-4 Derived Physiological Reactive Oxygen Species (Ros) Regulate Bmp-2-Induced Bone Remodeling; 2010 Jan. (International Conference on Advances in Free Radicals Research, Natural Products, Antioxidants and Radioprotectors in Health; vol. IL10).
|
| Mandal C, Ganapathy S, Ghosh-Choudhury G, Ghosh-Choudhury N. BMP-2-stimulated NOX4-PI 3 kinase-Akt signaling axis induces Ostoblast (OB) differentiation; 2009 Sep. (ASBMR 31st Annual Meeting, Denver, Colorado).
|
| Mandal C, Ghosh-Choudhury G, Yoneda T, Ghosh-Choudhury N. Omega-3 fatty acids (OFAs) intercept miR-21 and miR-214 targeting PTEN to prevent breast cancer bone metastasis; 2009 Sep. (ASBMR 31st Annual Meeting, Denver, Colorado).
|
