Abstract |
| Das F, Bera A, Ghosh-Choudhury N, Mariappan MM, Kasinath BS, Ghosh-Choudhury G. Hydrophobic motif site phosphorylation of protein kinase C beta II by mTORC2 regulates high glucose-induced mesangial cell hypertrophy; 2015 Jan. (J Am Soc Nephrol; vol. Suppl, no. 26).
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| Bera A, Das F, Ghosh-Choudhury N, Kasinath BS, Abboud HE, Ghosh-Choudhury G. Rictor-PDED4 interaction controlled by microRNA 21 contributes to renal cancer cell invasion; 2014 Jan. (J Am Soc Nephrol; vol. 25).
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| Das F, Bera A, Ghosh-Choudhury N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. mTOR component deptor contributes to TGFbeta induced collagen I alpha2 expression in proximal tubular epithelial cells; 2014 Jan. (J Am Soc Nephrol; vol. 25).
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| Bera A, Das F, Mariappan MM, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. microRNA-214 regulates mesangial cell (MC) hypertrophy and matrix expansion through PTEN; 2013 Jan. (J Am Soc Nephrol).
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| Das F, Bera A, Ghosh-Choudhury N, Kasinath BS, Abboud HE, Ghosh-Choudhury G. PDGF launches mesangial cell proliferation via a positive feedback loop involving EKK5 and Akt downstream of PI kinase; 2013 Jan. (J Am Soc Nephrol).
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| Bera A, Dey N, Das F, Kasinath BS, Abboud HE, Ghosh-Choudhury N, Ghosh-Choudhury G. microRNA-21-dependent positive feedback loop involving NFkappaB (NFkB) regulates renal cancer cell proliferation; 2012 Dec. (J Am Soc Nephrol; vol. 23).
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| Das F, Ghosh-Choudhury N, Dey N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. A signal relay from transforming growth factor beta (TGFb)-stimulated Smad 3 to mTOR involves deptor suppression to force mesangial cell hypertrophy; 2012 Nov. (J Am Soc Nephrol; vol. 23).
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Journal Article |
| Das F, Ghosh-Choudhury N, Venkatesan B, Kasinath BS, Ghosh Choudhury G. PDGF Receptor-? Uses Akt/mTORC1 Signaling Node to Promote High Glucose-induced Renal Proximal Tubular Cell Collagen I (?2) Expression Am J Physiol Renal Physiol 2017 Apr;.
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| Das F, Ghosh-Choudhury N, Mariappan MM, Kasinath BS, Ghosh-Choudhury G. Hydrophobic Motif Site-phosphorylated Protein Kinase CβII between mTORC2 and Akt Regulates High Glucose-induced Mesangial Cell Hypertrophy Am J Physiol Cell Physiol 2016 Jan;310(7):C583-C596.
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| Mandal CC, Das F, Ganapathy S, Harris SE, Choudhury GG, Ghosh-Choudhury N. Bone Morphogenetic Protein-2 (BMP-2) Activates NFATc1 Transcription Factor via an Autoregulatory Loop Involving Smad/Akt/Ca2 Signaling J Biol Chem 2016 Jan;.
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| Das F, Dey N, Bera A, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. microRNA 214 Reduces IGF-1 Receptor Expression and Downstream mTORC1 signaling in renal carcinoma cells J Biol Chem 2016 Jan;291:14662-14676.
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| Das F, Bera A, Dey N, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression Cell Signalling 2015 Jan;27:1276-1285.
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| Bera A, Das F, Ghosh-Choudhury N, Li X, Pal S, Gorin Y, Kasinath BS, Abboud HE, Ghosh-Choudhury G. A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF Am J Physiol Cell Physiol 2014 Jun;306(11):C1089-C1100.
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| Bera A, Das F, Ghosh-Choudhury N, Kasinath BS, Abboud HE, Ghosh-Choudhury G. microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion Exp Cell Res 2014 Jan;328(1):99-117.
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| Das F, Bera A, Ghosh-Choudhury N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression PLoS One 2014 Jan;9(10).
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| Das F, Ghosh-Choudhury N, Dey N, Bera A, Mariappan MM, Kasinath BS, Ghosh-Choudhury G. High Glucose Forces a Positive Feed Back Loop Connecting Akt Kinase and FoxO1 to Activate mTORC1 for Mesangial Cell Hypertrophy and Matrix Protein Expression J Biol Chem 2014 Jan;289:32703-32716.
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| Bera, Ghosh-Choudhury N, Dey N, Das F, Kasinath BS, Abboud HE, Choudhury GG. NFkB-Mediated Cyclin D1 Expression By microRNA-21 Influences Renal Cancer Cell Proliferation Cell Signal 2013 Dec;25(12):2575-2586.
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| Ghosh-Choudhury N, Mandal CC, Das F, Ganapathy S, Ahuja SS, Ghosh-Choudhury G. c-Abl-dependent molecular circuitry involving Smad5 and phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2-induced osteogenesis J Biol Chem 2013 Aug;288(34):24503-24517.
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| Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Ghosh-Choudhury G. TGF Beta-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy Journal of Cell Physiology 2013 Jul;228(7):1617-1626.
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| Das Falguni, Ghosh-Choudhury N, Bera Amit, Dey N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. TGF beta integrates SMAD 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy J Biol Chem 2013 Mar;288(11):7756-7768.
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| Das F, Ghosh-Choudhury N, Bera A, Dey N, Abboud HE, Kasinath BS, Ghosh-Choudhury G. Transforming Growth Factor ? Integrates Smad 3 to Mechanistic Target of Rapamycin Complexes to Arrest Deptor Abundance for Glomerular Mesangial Cell Hypertrophy Journal of Biological Chemistry 2013 Feb;288:7756-7768.
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| Das F, Ghosh-Choudhury N, Bera A, Dey N, Abboud HE, Kasinath BS, Ghosh Choudhury G. TGF? integrates SMAD 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy J Biol Chem 2013 Jan;288(11):7756-7768.
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| Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Choudhury GG. TGF?-induced PI 3 kinase-dependent MNK-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy J Cell Physiol [Epub ahead of print] 2013 Jan;.
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| Dey N, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. TGF?-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion PLoS One 2012 Aug;7(8).
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| Dey N, Ghosh-Choudhury N, Kasinath BS, Choudhury GG. TGF?-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion PLoS One 2012 Aug;7(8).
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| Mandal CC, Ghosh-Choudhury T, Dey N, Ghosh Choudhury G, Ghosh-Choudhury N. miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression Carcinogenesis 2012 Aug;.
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| Dey N, Das F, Ghosh-Choudhury N, Mandal CC, Parekh DJ, Block K, Kasinath BS, Abboud HE, Ghosh-Choudhury G. microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion PLoS One 2012 Jun;7(6).
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| Das F, Ghosh-Choudhury N, Dey N, Mandal CC, Mahimainathan L, Kasinath BS, Abboud HE, Choudhury GG. Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase J Biol Chem 2012 Feb;287(6):3808-3822.
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| Das F, Ghosh-Choudhury N, Dey N, Mandal CC, Mahimainathan L, Kasinath BS, Abboud HE, Choudhury GG. Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase J Biol Chem 2012 Feb;287(6):3808-22.
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| Dey N, Das F, Ghosh-Choudhury N, Mandal CC, Parekh DJ, Block K, Kasinath BS, Abboud HE, Choudhury GG. microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion PLoS One 2012 Jan;7(6).
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| Das F, Dey N, Venkatesan B, Kasinath BS, Ghosh-Choudhury N, Ghosh-Choudhury G. High glucose upregulation of early-onset Parkinson`s disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy Cell Signal 2011 Aug;23(8):1311-1319.
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| Dey N, Das F, Mariappan MM, Mandal CC, Ghosh-Choudhury N, Kasinath BS, Ghosh-Choudhury G. MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes J Biol Chem 2011 Jul;286(29):25586-25603.
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