Clark, Robert A.School of Medicine |
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| 8/2006 - Present | Assistant Vice President for Clinical Research and Director, Institute for Integration of Medicine and Science | University of Texas Health Science Center at San Antonio, San Antonio, TX |
| 8/2006 - Present | Professor and Associate Chair for Research | University of Texas Health Science Center at San Antonio, Medicine, San Antonio, TX |
| 9/1994 - Present | Professor | University of Texas Health Science Center at San Antonio, Physiology, San Antonio, TX |
| 7/1994 - Present | Attending Physician | University Hospital, University Health System, San Antonio, TX |
| 7/1994 - Present | Staff Physician | South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1973 | Residency | Chief Resident in Medicine | Harborview Medical Center Seattle , WA |
| 1972 | Postdoctoral Fellowship | Infectious Diseases | Laboratory of Clinical Investigation, NIAID, NIH Bethesda , MD |
| 1969 | Residency | Resident in Medicine | Columbia Presbyterian Medical Center New York , NY |
| 1968 | Internship | Medicine | University of Washington Hospital Seattle , WA |
| 1967 | MD | Medicine (Alpha Omega Alpha) | Columbia University, College of Physicians and Surgeons New York , NY |
| 1963 | AB | Mathematics (Magna Cum Laude) | Syracuse University Syracuse , NY |
Biology of Aging- Basic research on biochemical and cellular pathways involved in the aging process. |
Calcium-Binding Proteins- Basic research on structure, function, and regulation of endoplasmic reticulum calcium-binding proteins. |
Infectious Diseases- Clinical infectious diseases. |
Inflammation- Basic research on mechanisms of the acute inflammatory response. |
Internal Medicine- Clinical general internal medicine. |
Neurodegenerative Disorders- Basic research on the biochemical and cellular pathways involved in neurodegenerative disorders, especially Parkinson''s disease. |
Reactive Oxygen Species- Basic research on the mechanisms of generation of reactive oxygen species and their role in antimicrobial function, tissue injury, degenerative diseases, and aging. |
| Date | Description | Institution | # Students |
| 4/2005 - Present | Membership on Supervising Committee | University of Texas Health Science Center | |
| 2/2004 - Present | Post-Doctoral Student Supervision | University of Texas Health Science Center at San Anotnio | |
| 7/1994 - Present | Intro to Clinical Medicine | The University of Texas Health Science Center | 20 students |
| 7/1994 - Present | Medicine Clerkship (gen) | The University of Texas Health Science Center | 2 students |
| 7/1994 - Present | Clin Infectious Disease | The University of Texas Health Science Center | 4 students |
Journal Article |
| Venkatesan B, Prabhu SD, Venkatachalam K, Mummidi S, Valente AJ, Clark RA, Delafontaine P, Chandrasekar B. WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death Cell Signal 2010 May;22(5):809-820. |
| El Jamali A, Valente AJ, Clark RA. Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway Free Radic Biol Med 2010 Jan;:798-810. |
| Venkatachalam K, Venkatesan B, Valente AJ, Melby PC, Nandish S, Reusch JE, Clark RA, Chandrasekar B. WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death J Biol Chem 2009 May;284(21):14414-14427. |
Federal |
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| Funding Agency | Department of Veterans Affairs |
| Title | Redox Regulation of Phagocyte NOX2 in Inflammation and Aging |
| Status | Active |
| Period | 7/2010 - 6/2014 |
| Role | Principal Investigator |
| Grant Detail | The goals of this project are to characterize the molecular signaling pathways by which hydrogen peroxide activates superoxide generation by phagocyte NOX2 and assess the aberrant regulation of this pathway associated with aging. |
| Funding Agency | NIH/NCRR |
| Title | Institute for Integration of Medicine & Science (IIMS): A Partnership to Improve Health |
| Status | Active |
| Period | 5/2008 - 4/2013 |
| Role | Principal Investigator |
| Grant Detail | This Clinical and Translational Science Award (CTSA) provides a broad range of infrastructure support across the institution and its CTSA partners. |
| Funding Agency | NIH / NCRR |
| Title | Institute for Integration of Medicine & Science: A Partnership to Improve Health (CTSA KL2) |
| Status | Active |
| Period | 5/2008 - 4/2013 |
| Role | Principal Investigator |
| Grant Detail | This research career development award represents the KL2 component of the Clinical and Translational Science Award. The goal is to support the career development of promising young clinical / translational investigators. |
| Funding Agency | NIH/NHLBI |
| Title | Pathobiology of Occlusive Vascular Disease |
| Status | Complete |
| Period | 9/2007 - 8/2012 |
| Role | Co-Investigator |
| Grant Detail | This NIH training grant supports postdoctoral training in the area of occlusive cardiovascular disease, inflammation, and degenerative disorders of cardiovascular tissues. |