Clark, Robert A.School of Medicine |
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| 9/2012 - Present | Professor | UTHSCSA, Medicine, San Antonio, TX |
| 8/2006 - Present | Assistant Vice President for Clinical Research and Director, Institute for Integration of Medicine and Science | University of Texas Health Science Center at San Antonio, San Antonio, TX |
| 9/1994 - Present | Professor | University of Texas Health Science Center at San Antonio, Physiology, San Antonio, TX |
| 7/1994 - Present | Staff Physician | South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX |
| 7/1994 - Present | Attending Physician | University Hospital, University Health System, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1967 | MD | Medicine (Alpha Omega Alpha) | Columbia University, College of Physicians and Surgeons New York , NY |
| 1963 | AB | Mathematics (Magna Cum Laude) | Syracuse University Syracuse , NY |
| Internship | Medicine | University of Washington Hospital Seattle , WA |
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| Postdoctoral Fellowship | Infectious Diseases | Laboratory of Clinical Investigation, NIAID, NIH Bethesda , MD |
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| Residency | Chief Resident in Medicine | Harborview Medical Center Seattle , WA |
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| Residency | Resident in Medicine | Columbia Presbyterian Medical Center New York , NY |
Biology of Aging- Basic research on biochemical and cellular pathways involved in the aging process. |
Calcium-Binding Proteins- Basic research on structure, function, and regulation of endoplasmic reticulum calcium-binding proteins. |
Infectious Diseases- Clinical infectious diseases. |
Inflammation- Basic research on mechanisms of the acute inflammatory response. |
Internal Medicine- Clinical general internal medicine. |
Neurodegenerative Disorders- Basic research on the biochemical and cellular pathways involved in neurodegenerative disorders, especially Parkinson's disease. |
Reactive Oxygen Species- Basic research on the mechanisms of generation of reactive oxygen species and their role in antimicrobial function, tissue injury, degenerative diseases, and aging. |
| Date | Description | Institution | # Students |
| 9/2012 - Present | Post-Doctoral Student Supervision | UTHSCSA | |
| 7/1994 - Present | Clin Infectious Disease | The University of Texas Health Science Center | 4 students |
Journal Article |
| He W, Jimenez F, Martinez H, Harper NL, Manoharan MS, Carillo A, Ingale P, Liu Y, Ahuja SS, Clark RA, Rather CG, Ramirez DA, Andrews CP, Jacobs RL, Ahuja SK. Cockroach sensitization mitigates allergic rhinoconjunctivitis symptom severity in patients allergic to house dust mites and pollen J Allergy Clin Immunol 2015 Sep;136(3):658-666. |
| Gornalusse G, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan M, Avadhanam N, Murthy KK, Martinez H, Molano Murillo AM, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich L, Karim SA, Martin JN, Deeks SJ, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung`u T, Hunt PW, He W, Ahuja SK. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor Proc Natl Acad Sci (USA) 2015 Aug;112(34):E4762-E4771. |
| de Figueiredo ASP, Salmon A, Bruno F, Jimenez F, Martinez HG, Halade GV, Ahuja SS, Clark RA, DeFronzo RA, Abboud HE, El Jamali A. Nox2 mediates skeletal muscle insulin resistance induced by a high-fat diet J Biol Chem 2015 Jan;290(21):13427-13439. |
Federal |
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| Funding Agency | NIH/NHLBI |
| Title | Pathobiology of Occlusive Vascular Disease (Program Director - James Stockand) |
| Status | Active |
| Period | 9/2007 - 8/2022 |
| Role | Contributor |
| Grant Detail | This NIH training grant supports postdoctoral training in the area of occlusive cardiovascular disease, inflammation, and degenerative disorders of cardiovascular tissues. |
| Funding Agency | Veterans Health Administration |
| Title | Analysis of Olfactory Dysfunction for Early Diagnosis of Parkinson`s Disease |
| Status | Active |
| Period | 4/2016 - 3/2020 |
| Role | Principal Investigator |
| Grant Detail | This project will define the basis for olfactory dysfunction in early Parkinson?s disease in a genetic murine model employing expertise in olfaction, neurodegeneration, oxidative stress, neurobehavioral testing, and advanced imaging technologies. |
| Funding Agency | Department of Veterans Affairs |
| Title | Macrophage-Mediated Gene Delivery of Neurotrophic Factors for Parkinson`s Disease |
| Status | Active |
| Period | 10/2011 - 9/2019 |
| Role | Co-Investigator |
| Grant Detail | Using a chronic MPTP mouse model and regulatable glial-derived neurotrophic factor (GDNF)-expressing lentivectors, this project explores the efficacy and safety of hematopoietic stem cell-based macrophage-mediated GDNF gene therapy as a potential approach to Parkinson?s disease. |