UTHSCSA Faculty Profiles v1.0

DeFronzo, Ralph A

School of Medicine
(210) 567-6691

My major interests focus on the pathogenesis and treatment of type 2 diabetes mellitus, the central role of insulin resistance in the metabolic-cardiovascular cluster of disorders-known collectively as the Insulin Resistance Syndrome, and the etiology and treatment of diabetic nephropathy. Using the euglycemic insulin clamp technique in combination with radioisotope turnover methodology, limb catheterization, indirect calorimetry, and muscle biopsy, I have helped to define the biochemical and molecular disturbances responsible for insulin resistance in type 2 diabetes mellitus.

12/1994 - Present Deputy Director Texas Diabetes Institute, San Antonio, TX
12/1988 - Present Staff Physician South Texas Veterans Health Care System - Audie L. Murphy Division, San Antonio, TX
9/1988 - Present Professor of Medicine UTHSCSA, Medicine/Diabetes, San Antonio, TX
9/1988 - Present Director, Diabetes Research Unit Diabetes Research Unit, Barrter Research Unit, UTHSCSA, San Antonio, TX
9/1988 - Present Division Chief, Diabetes UTHSCSA, Medicine/Diabetes, San Antonio, TX