UTHSCSA Faculty Profiles v1.0
Denny, Ph.D., John Bernard
School of Medicine
Ophthalmology
(210) 567-8411
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| 9/2010 - Present |
Associate Professor |
University of Texas Health Science Center at San Antonio, Ophthalmology, San Antonio, TX |
| 2/2008 - Present |
Clara R. Brundage Foundation Interim Professor in Retina Degeneration Research |
University of Texas Health Science Center at San Antonio, Ophthalmology, San Antonio, TX |
| Year |
Degree |
Discipline |
Institution |
| 1985 |
Post Doctoral |
Biochemistry/Cell Biology |
Rockefeller University/Gunter Blobel Laboratory
New York , NY |
| 1982 |
PhD |
Biochemistry |
University of Florida, Gainesville
Gainesville , FL |
| 1977 |
MS |
Pharmacology |
University of Texas Health Science Center at Dallas
Dallas , TX |
| 1975 |
BS |
Pharmacy |
University of Texas at Austin
Austin , TX |
Protein biochemistry in the retina -
My research deals with the biochemistry and cell biology of neuronal growth in the retina. It utilizes standard biochemical techniques to study the function of various proteins that participate in the mechanism of nerve growth. A retinal ganglion cell line (RGC-5), the mouse neuroblastoma cell line N1E-115, retinal explants, and primary cultures of retinal ganglion cells are used to study how the cells might be induced to regenerate following damage. Similar damage ocurs in glaucoma and causes retinal ganglion cell death and blindness. |
Journal Article |
| Ollom, CM, Denny JB. A crosslinking analysis of GAP-43 interactions with other proteins in differentiated N1E-115 cells Int J Mol Sci 2008 Sep;9:1753-1771.
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| Denny JB. Protein palmitoylation in neuronal growth and plasticity Current Topics in Peptide & Protein Research 2008 Jan;9:57-69.
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Book Chapter |
| Denny, JB. The Cell Biology of Neuroblastoma. In: John Denny, Ph.D. Neuroblastoma. University Campus STeP Ri, Rijeka, Croatia: Invega Open Access Publisher; 2011. |
Private |
| Funding Agency |
Clara R. Brundage Foundation |
| Title |
Clara R. Brundage Foundation Interim Professorship in Retina Degeneration Research |
| Status |
Active |
| Period |
2/2008 - Present |
| Role |
Principal Investigator |
| Grant Detail |
|
| Funding Agency |
San Antonio Area Foundation |
| Title |
Nogo, oncomodulin, and optic nerve regeneration |
| Status |
Complete |
| Period |
6/2010 - 5/2011 |
| Role |
Principal Investigator |
| Grant Detail |
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