UTHSCSA Faculty Profiles v1.0
Denny, John Bernard
School of Medicine
Ophthalmology
(210) 567-8439
denny@uthscsa.edu
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| 2/2008 - Present |
Clara R. Brundage Foundation Interim Professor in Retina Degeneration Research |
University of Texas Health Science Center at San Antonio, Ophthalmology, San Antonio, TX |
| Year |
Degree |
Discipline |
Institution |
| 1985 |
Post Doctoral |
Biochemistry/Cell Biology |
Rockefeller University/Gunter Blobel Laboratory
New York , NY |
| 1982 |
PhD |
Biochemistry |
University of Florida, Gainesville
Gainesville , FL |
| 1977 |
MS |
Pharmacology |
University of Texas Health Science Center at Dallas
Dallas , TX |
| 1975 |
BS |
Pharmacy |
University of Texas at Austin
Austin , TX |
Protein biochemistry in the retina -
My research deals with the biochemistry and cell biology of neuronal growth in the retina. It utilizes standard biochemical techniques to study the function of various proteins that participate in the mechanism of nerve growth. A retinal ganglion cell line (RGC-5), retinal explants, and primary cultures of retinal ganglion cells are used to study how the cells might be induced to regenerate following damage. Similar damage ocurs in glaucoma and causes retinal ganglion cell death and blindness. |
Journal Article |
| Denny JB. Protein palmitoylation in neuronal growth and plasticity, in press Current Topics in Peptide and Protein Res 2009 Jan;.
|
| Ollom, Callise M, Denny JB. A crosslinking analysis of GAP-43 interactions with other proteins in differentiated N1E-115 cells Int J Mol Sci 2008 Sep;9:1753-1771.
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| Denny JB. Molecular mechanisms, biological actions, and neuropharmacology of the growth-associated protein GAP-43 Current Neuropharmacology 2006 Oct;4:293-304.
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| Denny JB. Growth-associated protein of 43 kDa (GAP-43) is cleaved nonprocessively by the 20S proteasome Eur J Biochem 2004 Jun;271(12):2480-2493.
|
Private |
| Funding Agency |
Clara R. Brundage Foundation |
| Title |
Clara R. Brundage Foundation Interim Professorship in Retina Degeneration Research |
| Status |
Active |
| Period |
2/2008 - Present |
| Role |
Principal Investigator |
| Grant Detail |
|
| Funding Agency |
San Antonio Area Foundation |
| Title |
Optic Nerve Regeneration in Glaucoma |
| Status |
Complete |
| Period |
6/2008 - 5/2009 |
| Role |
Principal Investigator |
| Grant Detail |
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