Journal Article |
| Thangasamy A, Rogge J, Krishnegowda NK, Freeman JW, Ammanamanchi S. Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor mediated cancer cell invasion J Biol Chem 2011 Jul;.
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| Zhao, S., Wang, Y., Cao, L., Ouellette, M.M. and Freeman, JW. Expression of oncogenic K-ras and loss of Smad4 synergize to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells International Journal of Cancer 2010 Jan;127:2076-2087.
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| Freeman JW, Wang Y, Giles FJ. Epigenetic modulation and attacking the hedgehog pathway: potentially synergistic therapeutic targets for pancreatic cancer Cancer Biol Ther 2009 Jul;8(14):1340-1342.
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| Zhao S, Ammanamanchi S, Brattain M, Cao L, Thangasamy A, Wang J, Freeman JW. Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells J Biol Chem 2008 Apr;283(17):11293-11301.
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| Zhao S, Venkatasubbarao K, Lazor JW, Sperry J, Jin C, Cao L, Freeman JW, Kolaparthi V. Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells Cancer Res 2008 Jan;68(11):4221-4228.
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Abstract |
| Chen Chen, Shujie Zhao, Lin Cao and James W. Freeman. CD44/c-MET signaling is required for maintaining an EMT phenotype and stemness of a highly tumorigenic pancreatic cancer cell variant isolated from Capan-2; 2012 Nov. (Adv Cells, Cancer Ther., South Padre Island, Texas).
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| Jingjing Gong, Jianping Xie, Izhar Singh Batth, James W Freeman, Divya Chakravarthy and Addanki P Kumar. Disruption of NF-kappaB/Stat3 interaction as a potential therapeutic avenue for pancreatic cancer management; 2012 Jun. (AACR, Pancreatic Cancer Meeting).
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| Jingjing Gong, James W Freeman, Addanki P Kumar. Interaction between Jak/Stat3 and ROS generation in pancreatic cancer; 2011 Nov. (Adv Cells, Cancer Ther., South Padre Island, Texas).
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| Jingjing Gong, James W Freeman and Addanki P Kumar. NF-kappaB and Stat3 interaction: a potential target for pancreatic cancer management; 2010 Nov. (Adv Cells, Cancer Ther., South Padre Island, Texas).
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| Freeman J. Enhanced inhibition of proliferation of pancreatic cancer cells by combination of Gemcitabine and Phellodendron amurense bark extract: target identification; 2010 Apr. (Proc American Association Cancer Research).
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| 61. Jingjing Gong, James W Freeman and Addanki P Kumar. Prostaglandin signaling: Target for pancreatic cancer; 2009 Nov. (Adv Cells, Cancer Ther. South Padre Island, Texas).
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Not Specified |
| Peterson L, Zhao S, Kolaparthi V, Freeman J. Knockdown of STAT3 inhibits growth and enhances response to gemcitabine in an orthotopic model of human pancreatic 2012 Jun;.
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| Bera A, VenkataSubbaRao K, Zhao S, Peterson L, Freeman J. Gemcitabine resistance is associated with EMT, expression of cancer stem cell markers and a specific miRNA profile in the human pancreatic cancer cell line BxPC3 2012 May;.
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