UTHSCSA Faculty Profiles v1.0

Kellogg, Dean L. Jr.

School of Medicine
Medicine
(210) 617-5197
kelloggd@uthscsa.edu

Dean L. Kellogg, Jr., MD, Ph.D., is a tenured Professor in the Departments of Medicine and Physiology at the University of Texas Health Science Center at San Antonio (UTHSCSA) and an Adjunct Professor of Pharmacy at the University of Texas at Austin. He is also a member of the Geriatric Research, Education, and Clinical Center (GRECC) at the South Texas Veterans Health Care System (STVHCS) and the Barshop Institute at UTHSCSA.

Dr. Kellogg`s research roles are as the Principal Investigator in several translational projects to explore anti-aging effects of rapamycin, acarbose, and other potential anti-aging pharmaceuticals in humans. These projects involve exploring the effects of anti-aging agents on mechanisms of physical performance, cognitive, and cardiovascular function. In addition, changes in oxidative stress levels and altered skeletal muscle function in human subjects are being explored. Collaborative projects are exploring immunomodulatory effects of rapamycin on responses to vaccines and on overall immunological function in healthy older (70-95yo) volunteers. In addition, he is continuing his work on human cardiovascular and thermoregulatory physiology with studies in spinal cord injured patients in collaborative studies with junior faculty from the Department of Rehabilitation.

Dr. Kellogg`s teaching duties involve the physiology and mechanisms of aging as well as geriatric clinical pharmacology. These duties have been performed within the UTHSCSA School of Medicine, the School of Dentistry, the School of Allied Health, and UT-Austin School of Pharmacy. His clinical teaching duties have been performed in the Geriatric Evaluation and Management Clinic (GEM), the Former Prisoner of War Clinic (FPOW Clinic), and the STVHCS Spinal Cord Injury Clinic. Dr Kellogg`s is the current mentor for Dr M.B Trbovich and responsible for her training as a career scientist through a 5 year VA Career Development Ward.

Dr. Kellogg's service duties include Co-leadership of the San Antonio Older Americans Independence Center's Clinical Research Core (RC-2). As such he has played a major role in developing, initiating, and conducting the overall operation of the SA OAIC so as to: 1) assist basic and clinical investigators in developing rigorous and appropriately powered clinical studies and trial concepts that will lead to innovative approaches to improve healthspan and lifespan; 2) facilitate implementation and execution of translational human studies and clinical trials by investigators; 3) provide expertise and coordinated access to resources and technology in both our OAIC and facilities throughout our institution to maximize the depth of phenotypic characterization relevant to aging in trial outcomes; 4) provide training in clinical research for early-stage faculty and those new to clinical research. The RC2 Core provides research project consultation and planning, assists with safety and regulatory compliance processes, facilitates subject recruitment and retention, and coordinates relationships with other relevant OAIC Cores and Core facilities. Importantly, RC2 is critical to the OAIC`s development of a clinical focus to conduct clinical research in geriatrics with emphasis on transformative translational research to advance discoveries from basic aging research to clinical trials and ultimately to clinical geriatrics. We also train early-career investigators, and partner with other OAICs, institutions, and the public to advance translational aging research. This Core integrates a number of important OAIC core functions to ensure efficient trial design and execution, including integrating studies with the OAIC Biostatistics and Data Management Core (RC-3), the Research Career Development Core (RCDC), and the Pilot and Exploratory Studies Core (PESC). RC-2 works with the Pre-Clinical Core (RC-1) so that studies conducted by both cores are compatible and thereby facilitate translation into subsequent human trials. His current clinical services are an as Attending Physician in the Geriatric Evaluation and Management Clinic (GEM), the Former Prisoner of War Clinic (FPOW Clinic), and the STVHCS Spinal Cord Injury Clinic where he directs care for veterans enrolled in the South Texas Veterans Health Care System.

1/2016 - Present Attending Physcian Spinal Cord Injury Clinic, STVHCS, San Antonio, TX
7/2010 - Present Professor of Pharmacy (Adjunct Appointment) UT Austin, Pharmacy, Austin, TX
9/2007 - Present Professor of Medicine UTHSCSA, Medicine, San Antonio, TX
9/2007 - Present Professor of Physiology (Cross Appointment) UTHSCSA, Physiology, San Antonio, TX
7/1994 - Present Member, Medical Staff STVHCS, San Antonio, TX
7/1992 - Present Member, Medical Staff University Health System, San Antonio, TX
7/1992 - Present Attending Physician Extended Care Therapy Center, STVHCS, San Antonio, TX
7/1992 - Present Attending Physician Geriatric Research, Education, and Clinical Center, STVHCS, San Antonio, TX
7/1992 - Present Attending Physician Fredric C. Barter General Clinical Research Center, STVHCS, San Antonio, TX