Kellogg, Dean L. Jr.School of Medicine |
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Dean L. Kellogg, Jr., MD, Ph.D., is a tenured Professor in the Departments of Medicine and Physiology at the University of Texas Health Science Center at San Antonio (UTHSCSA) and an Adjunct Professor of Pharmacy at the University of Texas at Austin. He is also a member of the Geriatric Research, Education, and Clinical Center (GRECC) at the South Texas Veterans Health Care System (STVHCS) and the Barshop Institute at UTHSCSA.
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| 7/2010 - Present | Professor of Pharmacy (Adjunct Appointment) | UT Austin, Pharmacy, Austin, TX |
| 9/2007 - Present | Professor of Physiology (Cross Appointment) | UTHSCSA, Physiology, San Antonio, TX |
| 9/2007 - Present | Professor of Medicine | UTHSCSA, Medicine, San Antonio, TX |
| 7/1994 - Present | Member, Medical Staff | STVHCS, San Antonio, TX |
| 7/1992 - Present | Attending Physician | Fredric C. Barter General Clinical Research Center, STVHCS, San Antonio, TX |
| 7/1992 - Present | Attending Physician | Geriatric Research, Education, and Clinical Center, STVHCS, San Antonio, TX |
| 7/1992 - Present | Attending Physician | Extended Care Therapy Center, STVHCS, San Antonio, TX |
| 7/1992 - Present | Member, Medical Staff | University Health System, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1994 | Postdoctoral Fellowship | Clinical Pharmacology | UTHSCSA San Antonio , TX |
| 1992 | Postdoctoral Fellowship | Geriatric Medicine | UTHSCSA San Antonio , TX |
| 1990 | Residency | Internal Medicine | UTHSCSA San Antonio , TX |
| 1989 | PhD | Physiology | UTHSCSA San Antonio , TX |
| 1986 | Internship | Internal Medicine | UTHSCSA San Antonio , TX |
| 1985 | MD | Medicine | UTHSCSA San Antonio , TX |
| 1980 | MA | Biology | University of Texas Austin , TX |
| 1977 | BA | Biology | Dartmouth College Hanover , NH |
| Immunomodulatory effects of Rapamycin in humans. |
| Effects of Rapamycin on the vasculature in humans. |
| Mechanisms of Nitric Oxide control of the vasculature in humans. |
| Alteration of mechanisms of vasoconstriction and vasodilation by menopause in humans |
| Alteration of mechanisms of vasoconstriction and vasodilation by hypertension in humans |
| Alteration of thermoregulatory reflexes by hypertension and diabetes in humans |
| Elucidation of the co-transmitter system that effects cutaneous active vasodilation in humans |
| Date | Description | Institution | # Students |
| 1/2010 - Present | 60220 PHR 253D: General Pathology | 60 students | |
| 2 hour-Spring Semester Class for 100 students at University of Texas at Austin | |||
| 7/2001 - Present | General Pathology | The University of Texas Health Science Center | |
| 2 hour - Spring Summer for 30 students | |||
| 6/2001 - Present | OT 5025 Occupational Therapy | 30 students | |
| 2 hour - Summer Semester | |||
| 7/1999 - Present | Physiology | The University of Texas Health Science Center | |
| Medical Physiology; 2 hour - spring semester for 200 students | |||
| 7/1997 - Present | Clinical Pharmacology | The University of Texas Health Science Center | |
| MS-4 elective; GS/G 4 hrs/month for 7 months (6-12 students) | |||
| 1/1993 - Present | STVHCS/ALMVAH | ||
| 1/1992 - Present | Undergraduate Student Supervision | STVHCS/ALMVAH | |
| 1/1990 - Present | Undergraduate Student Supervision | UTHSCSA | |
Journal Article |
| Kellogg Jr DL, Zhao JL, Wu Y, Johnson JM. Nitric oxide and receptors for VIP and PACAP in cutaneous active vasodilation during heat stress in humans Journal of Applied Physiology 2012 Jan;113:1512-1518. |
| Kellogg Jr DL, Zhao Jl, Wu Y, Johnson JM. Role of Soluble Guanylyl Cyclase Activation in Cutaneous Vasodilation Induced by Whole Body Heat Stress and Local Warming in Humans Journal of Applied Physiology 2011 Jan;110:1406-1413. |
| Kellogg Jr DL, Zhao JL, Wu Y, Johnson JM. VIP/PACAP receptor mediation of cutaneous active vasodilation during heat stress in humans Journal of Applied Physiology 2010 Jan;109:95-100. |
| Johnson, JM, Kellogg Jr DL. Local Thermal Control of the Human Cutaneous Circulation Journal of Applied Physiology 2010 Jan;109:1229-1238. |
| Kellogg Jr DL, Zhao JL, Wu Y. Roles of Nitric Oxide Synthase Isoforms in Cutaneous Vasodilation Induced by Local Warming of the Skin and by Whole Body Heat Stress in Humans J Appl Physiol 2009 Jan;107:1438-1444. |
| Royall D, Gao J, Zhao M, Polk MJ, Kellogg Jr DL. Asymmetric Insular Function Predicts Positional Blood Pressure in Non-Demented Elderly J. Neuropsychiatry Clin. Neurosci 2009 Jan;21:173-180. |
| Kellogg Jr DL, Zhao JL, Wu Y. Endothelial nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo Am J Physiol Heart Circ Physiol 2008 Jul;295(1):123-129. |
| Kellogg Jr DL, Zhao JL, Wu Y. Neuronal nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo Journal of Physiology 2008 Jan;586(3):847-857. |
| Kellogg Jr DL. The cutaneous circulation as a model of generalized microvascular function: translational science impeded by need for regulatory reform J. Appl. Physiol 2008 Jan;105. |
Book Chapter |
| Kellogg Jr DL. Thermoregulation. In: Edited by Wolff, Goldsmtih, Katz, Gilchrist, Paller, Leffell. Fitzpatricks Dermatology in General Internal Medicine, 8th Edition. 2012. |
| Kellogg Jr DL. Chapter 92 Thermoregulation. In: Edited by Wolff, Goldsmith, Katz, Gilchrist, Paller, Leffell. Fitzpatricks Dermatology in General Internal Medicine, 7th Edition. 2008. |
Abstract |
| Zhao JL, Kellogg Jr DL, Wu Y, Johnson JM. VPAC2 and/or PAC1 receptors interact with NOS during heat stress in humans; 2010 Jan. (The FASEB J). |
| Kellogg Jr DL, Zhao JL, Wu Y, Johnson JM. cGMP is involved in cutaneous vasodilation in local skin warming in humans; 2010 Jan. (The FASEB J). |
| Kellogg Jr DL, Zhao J, Wu YB, Zhao K, Johnson JM. Soluble guanylyl cyclase and cutaneous active vasodilation during heat stress in humans; 2009 Jan. (FASEB J; vol. 23). |
| Kellogg Jr DL, Zhao JL, Wu Y. Roles of eNOS and nNOS in cutaneous vasodilation induced by local warming of the skin and by whole body heat stress in humans; 2008 Jan. (FASEB J; vol. 22). |
| Zhao JL, Kellogg Jr DL, Wu Y. VPAC1 and /Or PAC1 receptors Participate in cutaneous Active Vasodilation during Heat Stress in Humans; 2008 Jan. (FASEB J; vol. 22). |
Federal |
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| Funding Agency | NIH/NIA |
| Title | Translational Model Development: Rapamycin, Aging, and Endothelial Dysfunction |
| Status | Active |
| Period | 1/2012 - 1/2014 |
| Role | Principal Investigator |
| Grant Detail | This NIA R21 combines localized topical treatment of skin with non-invasive or minimally invasive pharmacological and physiological tests in humans in vivo to safely and rigorously initiate the translation of rapamycin from bench to bedside as a human anti-aging therapy. |
| Funding Agency | NIH / NHLBI |
| Title | Pathobiology of Occlusive Vascular Disease |
| Status | Complete |
| Period | 9/2007 - 8/2012 |
| Role | Contributor |
| Grant Detail | This NIH training grant supports postdoctoral training in the area of occlusive cardiovascular disease, inflammation, and degenerative disorders of cardiovascular tissues. |
| Funding Agency | NIH |
| Title | Mechanisms of Cutaneous Active Vasodilation in Humans |
| Status | Complete |
| Period | 8/2005 - 7/2010 |
| Role | Principal Investigator |
| Grant Detail | The aim of this project is to explore, using pharmacological tools, the mechanisms of action of the human cutaneous active vasodilator system. |
Private |
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| Funding Agency | Baptist Health Care System |
| Title | Effect Of Rapamycin On Muscle Strength And Physical Performance in Octogenarians |
| Status | Active |
| Period | 12/2012 - 12/2013 |
| Role | Co-Investigator |
| Grant Detail | Our aim is to assess potential benefits of rapamycin in ameliorating deterioration of physical and cognitive function in octogenarians. |
| Funding Agency | Clarimedix, Inc. |
| Title | Direct and Indirect Measures of the Effect of Light on Cutaneous Blood Flow |
| Status | Active |
| Period | 1/2012 - 1/2013 |
| Role | Co-Investigator |
| Grant Detail | This project will determine whether 959nm light activates conversion of nitrite to nitric oxide through the cyctochrome c oxidase pathway in the human cutaneous circulation. |
State |
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| Funding Agency | CTSA/IIMS Translational Research Grant |
| Title | Pilot Study to Assess Whether Rapamycin Will Improve Immunity in Octogenarians |
| Status | Active |
| Period | 1/2012 - 1/2013 |
| Role | Principal Investigator |
| Grant Detail | Our aim is to determine the safety of rapamycin and to assess potential benefits thereof in ameliorating immunosenescence in octogenarian humans. |