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Peters, Jay I MD

School of Medicine
Medicine
(210) 617-5256
peters@uthscsa.edu

Appointments Education Expertise Teaching Publications Grants

4/2009 - Present	Chief, Division of Pulmonary and Critical Care Medicine	University of Texas Health Science Center at San Antonio, Medicine, San Antonio, TX
1/2009 - Present	Adjunct Professor Pharmaceutics	University of Texas at Austin, Pharmacology, Austin, TX
9/1996 - Present	ACLS Instructor	South Texas Veterans Healthcare System, San Antonio, TX
9/1996 - Present	Chair, Cold Blue Committee	South Texas Veterans Health Care System, Medicine, San Antonio, TX
9/1996 - Present	Professor	The University of Texas Health Science Center at San Antonio, Medicine, San Antonio, TX
9/1996 - Present	Chair, Critical Care Committee	South Texas Veterans Health Care System, Medicine, San Antonio, TX
9/1994 - Present	Medical Director	University of Texas Health Science Center at San Antonio, Department of Respiratory Therapy, San Antonio, TX
8/1994 - Present	Medical Director	School of Allied Health, San Antonio, TX
6/1984 - Present	Staff Physician and Staff Physician	The South Texas Veterans Healthcare System, Audie L Murphy Division, Pulmonary Diseases and Critical Care, San Antonio, TX
6/1984 - Present	Assistant Foundation Scientist	Southwest Foundation for Biomedical Research, San Antonio, TX

Date	Description	Institution	# Students
11/2013 - Present	Grand Rounds - Asthma 2013:Pathogenesis, Therapies and Controversies	North Shore LIJ	100 students

1/2012 - Present	Pre-Doctoral Student Supervision	University of Texas at Austin

1/2012 - Present	Pre-Doctoral Student Supervision	University of Texas at Austin

9/2008 - Present	Dilemmas in the ICU	University of Texas Health Science Center at San Antonio	50 students
Medical School Ethics Presentation
7/2006 - Present	Adv Clin Eval Skills	The University of Texas Health Science Center

7/2006 - Present	On Becoming a Doctor Foundations	The University of Texas Health Science Center

6/2006 - Present	Internal Medicine Morning Report	University of Texas Health Science Center at San Antonio	50 students
Faculty discussion for daily intern and resident morning conference.
1/2006 - Present	Pre-Doctoral Student Supervision	University of Texas at Austin College of Pharmacy/UTHSCSA

8/2000 - Present	Medical Block Course Registratio	The University of Texas Health Science Center
MS-2 Pulmonary Lecture Series: Introduction to the Diagnosis and Management of Asthma
7/2000 - Present	Intro to Clin Medicine	The University of Texas Health Science Center
Annual Pulmonary ACES Course: Pre-clinical teaching using patients with a variety of pulmonary diseases (i.e., very severe chronic obstructive pulmonary disease, pulmonary fibrosis, and/or post-lung transplant) to emphasize physical exam techniques that emphasize the identification and diagnosis of pulmonary problems.
9/1996 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1994 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1993 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1992 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1988 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1988 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1985 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

9/1984 - Present	Post-Doctoral Student Supervision	University of Texas Health Science Center at San Antonio

7/1984 - Present	Off Campus	The University of Texas Health Science Center	10 students
Medicine Thoracic Clinic Attending, University Hospital-Downtown: 1/2 day clinic per week, 6-8 weeks, 5-6 contact hours/week.
7/1984 - Present	Post-Doctoral Student Supervision	The University of Texas Health Science Center at San Antonio and South TX Veterans Healthcare System

7/1984 - Present	Clinical Medicine II	The University of Texas Health Science Center	10 students
South Texas Veterans Healthcare System, Pulmonary Clinic Attending: 1/2 day clinic per week for 16 weeks, 5-6 contact hours per week.
7/1984 - Present	Clinical Chest Disease	The University of Texas Health Science Center	10 students

7/1984 - Present	Clinical Medicine	The University of Texas Health Science Center	20 students

Journal Article

Shivshankar P, Payan H, Calhoun C, William R, Jahgidair J, Levine S, Peters J, Jourdan Le Saux C. Inhaled Tacrolimus Modulates Fibrosis Development without Promoting Inflammation in Bleomycin-Injured Mouse Lungs Journal of Drug Delivery Science and Technology 2014 Sep;.

Wang YB, Watts AB, Peters JI, Liu S, Batra A, Williams RO. In Vitro and In Vivo Performance of Dry Powder Inhalation Formulations: Comparison of Particles Prepared by thin Film Freezing and Micronization. Epub AAPS PharmSciTech 2014 May;.

Hung JY, Horn, Diane, Woodruff, Kathleen, Prihoda, Thomas, LeSaux, Claude, Peters JI, Tio FO, Werner SL. Colony Stimulating Factor 1 Potentiates Lung Cancer Bone Metastasis Laboratory Investigation 2014 Jan;94(4):371-381.

Renda Soylemez Wiener, Ouellette DR, Edward Diamond, Vincent S. Fan, Janet R. Maurer, Richard A. Mularski, Peters JI, Scott D. Halpern. The Choosing Wisely Top Five List in Adult Pulmonary Medicine Chest 2014 Jan;.

Bayer J, Das NA, Basiden CE, Rani M, Schwacha MG, Sako EY, Williams RO, Peters JI, Johnson SB. Effect of Inhaled Tacrolimus on Ischemia Reperfusion Injury in a Rat Lung Transplant Model The Journal of Thoracic and Cardiovascular Surgery 2013 Sep;146(5):1213-1219.

Purvis T, Pollack M, Coalson JJ, McNeish L, Williams III RO, Peters JI. Efficacy of Tacrolimus Nanoparticles Using In Vitro Cellular Assays for Immune Function.(submitted) Respiratory & Critical Care Medicine 2013 Aug;.

Burks ML, Brooks EG, Hill VL, Peters JI, Wood PR. Assessing proxy reports: agreement between children with asthma and their caregivers on quality of life Ann Allergy Asthma Immunol 2013 Jul;111(1):14-19.

Wood PR, Hill VL, Burks ML, Peters JI, Singh H, Kannan TR, Vale S, Cagle MP, Principe MF, Baseman JB, Brooks EG. Mycoplasma pneumoniae in children with acute and refractory asthma Ann Allergy Asthma Immunol 2013 May;110:328-334.

Jagirdar J, Chikkamuniyappa, S, Sirohi, D., McCarthy MJ, Peters JI. Cystic lung lesions in Sjogren syndrome: analysis of lymphocyte subsets in tissue with clinico-radiologic-pathologic correlation Ann Diagn Pathol 2013 Feb;17(1):113-116.

Dugas HL, Peters JI, Robert O Williams III. Nebulization of Mycophenolate Mofetil Inhalation Suspension: Comparison with Oral and Pulmonary Administration of Cellcept International Journal of Pharmaceutics 2013 Jan;441(1-2):19-29.

H. Dugas, Peters JI, R.O. Williams III. Pulmonary Bioavailability of an Inhaled Mycophenolate Mofetil Suspension: Comparison with the Nebulization of IV Cellcept Solution Proceedings of the American Association of Pharmaceutical Scientists 2012 Oct;.

Burguete SR, Levine SM, Restrepo MI, Angel LF, Levine DJ, Coalson JJ, Peters JI. Lung transplantation for Williams-Campbell syndrome with a probable familial association Respir Care 2012 Sep;57(9):1505-1508.

Peters JI, Stupka JE, Singh H, Rossrucker J, Angel LF, Melo J, Levine SM. Status asthmaticus in the medical intensive care unit: A 30-year experience Respir Med 2012 Mar;106(3):344-348.

Burguete SR, Levine SM, Restrepo MI, Angel L, Levine DJ, Coalson JJ, Peters JI. A Role for Lung Transplantation in Williams-Campbell Syndrome Respiratory Care 2012 Jan;57(9):1505-1508.

Peters JI, Anzueto AR. Azithromycin once daily for 1 year reduced acute COPD exacerbations Annals of Internal Medicine ACP Journal Club 2012 Jan;156(2):1-10.

Peters JI, Stupka JE, Singh, Harjinder, Rossrucker, Jill, Angel L, Melo, Jairo, Levine SM. Status Asthmaticus in the Medical Intensive Care Unit: A Thirty Year Experience Respiratory Medicine 2012 Jan;106(3):344-348.

H.L. Dugas, Peters JI, S.A. Stavchansky, R.O. Williams III. Hydrolysis of Mycophenolate Mofetil in Human Lung Epithelial Cells, Microsomes and Cyosol Fractions Biochemical Pharmacology (submitted) 2012 Jan;.

Peters JI, Singh, H., Brooks EG, Diaz, J., Kannan TR, Coalson JJ, Baseman, J, Cagle, M., Baseman JB. Persistence of Community-Acquired Respiratory Distress Syndrome Toxin-Producing Mycoplasma pneumoniae in Refractory Asthma Chest 2011 Aug;140(2):401-407.

Watts AB, Peters JI, Talbert RL, ODonnell KP, Coalson JJ, Williams RO. Preclinical evaluation of tacrolimus colloidal dispersion for inhalation Eur J Pharm Biopharm 2011 Feb;77(2):207-215.

Peters JI, McKinney JM, Smith B, Wood P, Forkner E, Galbreath AD. Impact of obesity in asthma: evidence from a large prospective disease management study Ann Allergy Asthma Immunol 2011 Jan;106(1):30-35.

Yang W, Owens DE, Peters JI, Williams RO III. Improved Bioavailability of Engineered Amorphous Nanostructured Compositions of Poorly Water-Soluable Drugs by Rapid-Freezing Particle Engineering Technology Drug Delivery Technology 2010 Oct;10(8):22-31.

Watts AB, Cline AM, Saad AR, Johnson SB, Peters JI, Williams RO. Characterization and pharmacokinetic analysis of tacrolimus dispersion for nebulization in a lung transplanted rodent model Int J Pharm 2010 Jan;384(1-2):46-52.

Karpel JP, Peters JI, Szema AM, Smith B, Anderson PJ. Differences in physicians self-reported knowledge of, attitudes toward, and responses to the black box warning on long-acting beta-agonists Ann Allergy Asthma Immunol 2009 Oct;103(4):304-310.

Hardy, RD, Coalson JJ, Peters, JI, Chaparro, A, Techasaensiri, C, Cantwell AM, Kannan TR, Baseman JB, Dube PH. Analysis of Pulmonary Inflammation and Function in the Mouse and Baboon after Exposure to Mycoplasma pneumoniae CARDS Toxin Public Library of Science (PLoS ONE) 2009 Oct;4(10).

Tolman JA, Nelson NA, Bosselmann S, Peters JI, Coalson JJ, Wiederhold NP, Williams RO. Dose tolerability of chronically inhaled voriconazole solution in rodents Int J Pharm 2009 Sep;379(1):25-31.

Tolman JA, Wiederhold NP, McConville JT, Najvar LK, Bocanegra R, Peters JI, Coalson JJ, Graybill JR, Patterson TF, Williams RO. Inhaled voriconazole for prevention of invasive pulmonary aspergillosis Antimicrob Agents Chemother 2009 Jun;53(6):2613-2615.

Shelledy DC, LeGrand TS, Gardner DD, Peters JI. A Randomized, Controlled Study to Evaluate the Role of an In-Home Asthma Disease Management Program Provided by Respiratory Therapists in Improving Outcomes and Reducing the Cost of Care Journal of Asthma 2009 Mar;46:194-201.

Watts AB, Williams RO, Peters JI. Recent developments in drug delivery to prolong allograft survival in lung transplant patients Drug Dev Ind Pharm 2009 Mar;35(3):259-271.

Galbreath AD, Smith B, Wood PR, Inscore S, Forkner E, Vazquez M, Fallot A, Ellis R, Peters JI. Assessing the Value of Disease Management: impact of 2 disease management strategies in an underserved asthma population Ann Allergy Asthma Immunol 2008 Dec;101:599-607.

Tolman JA, Nelson NA, Son YJ, Bosselman S, Wiederhold NP,Peters JI, McConville JT, Williams III RO. Characterization and Pharmacokinetic Analysis of Aerosolized Aqueous Voriconazole Solution European Journal of Pharmaceutics and Biopharmaceutics 2008 Dec;:199-205.

Book/Monograph

Peters JI, Shelledy, David, Editor and co- authored for four chapters. Textbook of Respiratory Care Burlington,Mass: Jones and Bartlet Learning; 2014.

Book Chapter

Burguete SR, DeArmond DT, Peters JI. Pneumothorax (in press). In: Fishman AP, Elias JA, Fishman JA, Grippi MA, Kaiser LR, Senior RM. Fishman''s Pulmonary Diseases and Disorders, 5th edition (in press). NY: McGraw Hill; 2013.

Peters JI, Levine SM. Introduction to Pulmonary Function Testing, Chapter 32 (In press). In: Edited by J.T. DiPiro, R. L. Tabert, G.C Yee, G.R. Matzke, B.G Wells, L.M. Posey. Pharmacotherapy: A Pathophysiologic Approach. 2013.

Maselli DJ, Peters JI, Adams SG. Chapter 26: Hemoptysis. In: Editors: James F Shanahan and Robert Pancotti. The Patient History: An evidence-Based Approach to Differential Diagnosis. New York City, NY: McGraw-Hill Companies Inc; 2012. p. 251-257.

Peters JI. Introduction to Pulmonary Function Testing (Chapter 27). In: Peters, JI , Levine, Stephanie M. Respiratory Disorders. 2009. p. 271-278.

Abstract

Yi-Bo Wang, Alan B. Watts, Peters JI, Robert O. Williams III. The Impact of Pulmonary Diseases on the Fate of Inhaled Medicines; 2014 Jan. (International Journal of Pharmaceutics; vol. 461, no. 1-2).

Bayer, J, Das NA, Baisden CE, Rani M, Schwacha MG, Sako EY, Williams, RO, Peters JI, Johnson SB. Effect of inhaled tacrolimus on ischemia reperfusion injury in rat lung transplant model: Minneapolis, MN; 2013 May. (The Journal of Thoracic and Cardiovascular Surgery; vol. 146, no. 5).

Watts, AB, Wang, Y, Carvalho, S, Peters JI, Williams, RO. A Comprehensive DPI Platform for Delivery of Small Molecules and Biologics; 2013 Jan. (American Thoracic International Conference Abstracts; vol. 276, no. A4114).

Alan B. Watts, Yi-Bo Wang, Levine SM, Peters JI, Robert O. Williams. Development of Inhaled Tacrolimus: Human Safety and Formulation Improvements; 2012 May. (Respiratory Drug Delivery 2012; vol. 3).

Le Saux CJ, P. Schivshankar, Payan H, R.O. Williams, J., Peters JI. Inhaled Tacrolimus Protects Mice From Bleomycin-Induced Lung Fibrosis; 2012 May. (American Thoracic Society International Meeting).

Peters JI. Impact of Omalizumab in Severe Asthmatics With Marked Elevation of IgE; 2011 Oct. (Chest; vol. 140, no. 4).

Levine SM, Singh H, Williams R, ODonnell K., Lang B, Wang Y, Anzueto AR, Talbert R., Peters JI. Safety and Tolerability of Single Dose Inhaled Tacrolimus in Healthy Subjects; 2011 Oct. (Chest Meeting Abstracts; vol. 140, no. 4).

Peters JI. Persistence of Mycoplasma pneumoniae (MP) in Patients With Refractory Asthma (RA); 2010 Oct. (Chest Meeting Abstracts; vol. 138, no. 4).

Vines DL, Sonetti D, Wettstein RB, Peters JI. A simple spontaneous breathing model used to evaluate oxygen mask performance; 2009 Oct. (Chest Meeting Abstracts).

Peters JI, Singh H, Cagle M, Kannan TR, Baseman JB, Baseman, JG. Prevalence of mycoplasma pneumoniae infection in acute exacerbations of asthma in pediatric and adult population; 2009 Oct. (Chest Meeting Abstracts).

Levine DJ, Coalson JJ, Pollack MS, Werner S, Babu RV, Levine SM, Johnson SB, Peters JI, Calhoon JH, De Armond DT, Angel LF. Detection of HLA-II-DQ donor-specific antibody (DSA) in lung transplant recipients (LTRS) is associated with severe histopathologic changes and impaired graft survival even in the absence of other DSAS and positive C4D-immunostaining; 2009 Oct. (Chest Meeting Abstracts).

Singh H, Peters JI, Morris M, Cagle M, Kannan TR, Baseman JG, Baseman JB. Distribution of a new serologic test for mycoplasma pneumoniae (MP) in a healthy population and a population presenting with acute exacerbation of asthma; 2009 Oct. (Chest Meeting Abstracts).

Peters JI, Singh H, Cagle M, Baseman JG, Baseman JB. Prevalence of Mycoplasma pneumoniae (MP) in Patients Hospitalized with Acute Exacerbation of Asthma (AEA); 2009 Apr. (Am. J. Respir. Crit. Care Med; vol. 179).

Peters JI, Gardner DD, Vines DL. Community aerosol device education study(CADE Study); 2008 Oct. (CHEST; vol. 134, no. s5500).

Sanchez J, Peters JI, Watts AB, Williams RB, Dube PH. Histological Changes in Ovalbumin Sensitized Mice Pretreated with Inhaled Cyclosporine; 2008 Oct. (CHEST; vol. 134).

Peters JI, Karpel JP, Szema AM, Smith B, Anderson P. Differences in physicians knowledge, attitudes and response to the black box warning on long-acting beta-agonists; 2008 Oct. (CHEST; vol. 134).

Peters JI, Watts A, Coalson J, Johnston K, Williams III R. Long-term safety of inhaled tacrolimus nanoparticles in rodent model; 2008 Oct. (CHEST; vol. 134).

Saad AR, Cline AM, Watts AB, Hsiung GE, Peters JI, Baisden CE, Levine DJ, Calhoon JH, Angel LF, Williams III R, Johnson SB. Nanoparticle tacrolimus inhalation in rat lung transplant model; 2008 Oct. (CHEST; vol. 134, no. 4).

Susanto IS, Sako EY, Anzueto AR, Levine SM, Peters JI, Cronin T, Jenkinson SG, Bryan C. Outcome of single lung transplants from the same donor: "Pulmonary Twinning"; 1995 Oct. (Chest; vol. 108, no. 3).

Review Article

Yi-Bo Wang, Alan B. Watts, Peters JI, Robert O. Williams III. The Impact of Pulmonary Diseases on the Fate of Inhaled Medicines International Journal of Pharmaceutics 2014 Jan;461(1-2):112-128.

Maselli DJ, Adams SG, Peters JI, Levine SM. Management of asthma during pregnancy Ther Adv Respir Dis 2013 Apr;7(2):87-100.

Maselli DJ, Adams S, Peters JI. The role of anti-infectives in the treatment of refractory asthma Ther Adv Respir Dis 2011 Dec;5(6):387-396.

Morales JO, Peters JI, Williams RO. Surfactants: their critical role in enhancing drug delivery to the lungs Ther Deliv 2011 May;2(5):623-641.

Carvalho TC, Peters JI, Williams RO. Influence of particle size on regional lung deposition--what evidence is there? Int J Pharm 2011 Mar;406(1-2):1-10.

Editorial

Maselli DJ, Peters JI. Five days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation Ann Intern Med 2013 Sep;159(6):5-5.

Adams SG, Peters JI. Amoxicillin/clavulanate vs placebo: more exacerbation cures, fewer recurrences in mild-to-moderate COPD Annals of Internal Medicine ACP Journal Club 2013 Mar;158(6):3-3.

Peters JI. Letter to Editor Chest Physician 2010 Mar;5(3).

Peters JI. Risks and Benefits of Long-acting Beta-agonists in Asthma. Evidence-Based Medicine for Primary Care and Internal Medicine American Journal of Medicine 2010 Jan;123:322-328.

Peters JI. Review: Formoterol increases serious adverse events in children and adults with chronic asthma Evid Based Med ACP Journal Club 2009 Jun;14(3):78-78.

Peters JI. Review: Systemic corticosteroids, antibiotics and noninvasive positive pressure ventilation are effective in acute COPD Annals of Internal Medicine ACP Journal Club 2008 Aug;149(2):13-13.

Electronic/Web Publication

Peters JI. Case Studies in COPD: Therapy and Prevention of Exacerbations, Self Study Educational Module 2013 Sep.

Not Specified

Maselli DJ, Peters JI. 5 days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation Ann Intern Med 2013 Sep;159(6):5-5.

Adams SG, Peters JI. ACP Journal Club. Amoxicillin/clavulanate vs placebo: more exacerbation cures, fewer recurrences in mild-to-moderate COPD Ann Intern Med 2013 Mar;158(6):3-3.

Federal
Funding Agency	NIH
Title	Genetic Epidemiology of Chronic Obstructive Pulmonary Disease
Status	Active
Period	9/2007 - Present
Role	Co-Investigator
Grant Detail	Genetic Epidemiology of Chronic Obstructive Pulmonary Disease. The original local grant was approximately $1.2 million. Renewal Pending- 7/1/2012-06/30/2017
Funding Agency	National Institute of Allergy and Infectious Disease (NIH)
Title	Mycoplasma Pneumoniae Infection in Patients with Chronic Asthma
Status	Active
Period	8/2006 - 7/2013
Role	Principal Investigator
Grant Detail	Dr. Peters funding is a subproject to Dr. Joel Basemans NIH Grant, Role of unique ADP-ribosylating vacuolating Mycoplasma pneumoniae toxin in asthma, Grant Number: U19AI070412.
Funding Agency	National Institute of Allergy and Infectious Disease (NIH)
Title	Mycoplasma Pneumoniae Infection in a Pediatric Population - NIAID Supplemental Grant to Project 3 (Recovery and Reinvestment Act)
Status	Active
Period	9/2009 - 9/2011
Role	Principal Investigator
Grant Detail	Dr. Peters directs and oversees Co-investigators in the assessment of Mycoplasma in a pediatric population and the use of exhaled cindensates as a diagnostic tool.
Private
Funding Agency	Merrell-Dow
Title	Use of Deflazocort in Chronic Asthma
Status	Active
Period	10/1990 - Present
Role	Principal Investigator
Grant Detail
State
Funding Agency	State of Texas, Texas Ignition Grant
Title	Development of Nanoparticles of Inhaled Tacrolimus
Status	Active
Period	7/2010 - 7/2014
Role	Co-Principal Investigator
Grant Detail	Creation of nanoparticles of Tacrolimus for retreatment of chronic rejection. Creation of nanoparticles of Tacrolimus for the treatment of chronic rejection and asthma (patent pending). University of Texas Health Sciences Center at San Antonio and University of Texas School of Pharmacy.
Funding Agency	University of Texas Health Science Center, CTSA Grant
Title	Inhaled Tacrolimus in the Prevention of Rejection After Lung Transplantation
Status	Active
Period	6/2011 - 6/2012
Role	Co-Principal Investigator
Grant Detail	Evaluation of nanoparticles of Tacrolimus for the prevention of acute rejection in a rodent lung transplant model.
Funding Agency	University of Texas Health Science Center, CTSA Grant
Title	Inhaled Tacrolimus in the Prevention of Pulmonary Fibrosis
Status	Active
Period	6/2011 - 6/2012
Role	Co-Principal Investigator
Grant Detail	Evaluation of nanoparticles of Tacrolimus for the treatment of pulmonary fibrosis in a Bleomycin-induced injury model in rodents.

Year	Degree	Discipline	Institution
1983	Postdoctoral Fellowship	Pulmonary/Critical Care/Infectious Disease (Pulmonary/Critical Care/Infectious Disease Fellowship)	Baylor College of Medicine Houston , TX
1980	Postdoctoral Fellowship	Internship and Residency (Infectious Diseases)	Baylor College of Medicine Houston , TX
1980	Residency	Chief Medical Resident (Chief Medical Resident, 7/80 - 12/80)	Baylor College of Medicine Houston , TX
1976	MD	Medicine (Alpha Omega Alpha)	Baylor College of Medicine Houston , TX
1973	BA	(Magna Cum Laude)	University of Texas at Austin Austin , TX
1970	BA	(Honors & Scholars Program)	Tulane University New Orleans , LA

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