| 3/2014 - Present |
Vice Chairman of Neonatology Services and Vice Chairman of Neonatology Services |
The University of Texas Health Sciences Center at San Antonio, Pediatrics, San Antonio, TX |
| 11/2009 - Present |
Neonatologist |
Community Medicine Associates, Pediatrics, San Antonio, TX |
| 9/2002 - Present |
Professor |
The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| 11/2000 - Present |
Medical Director |
Neonatal Intensive Care Unit, University Hospital, San Antonio, TX |
| 11/2000 - Present |
Chief, Division of Neonatology |
The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| 9/1996 - Present |
Tenure |
The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| 8/1989 - Present |
Medical Staff Member |
University Hospital, San Antonio, TX |
Developmental hormonal regulation -
Glucocorticoid and cAMP regulation of ENaC and surfactant proteins in cultured fetal lung explants and in ventilated preterm animals |
ENaC -
Molecular physiology of ENaC and surfactant proteins during positive-pressure ventilation in preterm animals |
Exogenous surfactant as a vehicle for IT drugs -
Exogenous surfactant as a vehicle for intratracheally administered drugs (e.g. antioxidants) |
Lung cytokines -
Cytokine Regulation of ENaC Signal Transduction in the developing lung |
Lung maturational agents -
Augmentation of surfactant therapy with antenatal and postnatal lung maturational agents |
Optical Imaging of Neonatal Intestinal Perfusion -
In collaboration with Spectros both non-human primate and human infant studies using near infrared and visible light spectroscopy to assess perfusion of the compromised neonatal intestine |
Postnatal glucocorticoids and BPD -
Glucocorticoid effects on lung function, lung development, surfactant metabolism, and protein leak in BPD |
Regulation of ductus arteriosus -
Regulation of ductus arteriosus remodeling by nitric oxide and prostaglandins in preterm animals of borderline viability |
Stem Cell Therapy of Neonatal Lung Disease -
In collaboration with Dr. Bernard Thebaud in Canada treating premature non-human primates with local and systemic stem cells to prevent chronic lung disease following mechanical ventilation |
Surfactant distribution and function -
Exogenous surfactant distribution and function |
VILI and surfactant -
Surfactant lipid and protein metabolism following lung injury in ventilated preterm and adult animals |
| Date |
Description |
Institution |
# Students |
| 7/2001 - Present |
Pediatric Resident Didactic Conference |
University of Texas Health Science Center |
10 students |
| Monthly didactics for residents and medical students on Mechanical Ventilation, Intestinal Obstruction in the Newborn, Ventilating the ELBW Infant, etc. (usually present 10-12 per year) |
| 7/1999 - Present |
Neonatology Fellowship Program |
University of Texas Health Science Center at San Antonio |
12 students |
| Charlene Crichton, Candace Campos, Judy Anderson, Jean Petershack, Shamim Mustafa, Cynthia Blanco, George Powers, Margarita Vasquez, Christine Bishop, Tim Biela |
| 7/1996 - Present |
Primary Care New Born Service |
University Hospital |
|
| 1 - 4 weeks per year, 40 hours per week |
| 7/1993 - Present |
Perinatal Morbidity Case Conference |
University Hospital |
|
| 40 weeks per year, 1 hour |
| 1/1990 - Present |
Neonatal Resuscitation Course |
University Hospital |
|
| 2 days per year |
| 1/1990 - Present |
Neonatal Skills Workshop |
University Hospital |
|
| 1 day per year |
| 7/1989 - Present |
NICU Rotation |
NICU, University Hospital |
|
| 4-8 weeks per year, 40 hours per week |
Abstract |
| Siddiqui S, Mustafa SB, Vasquez MM, Werner S, Seidner SR. Mechanical Ventilation Alters the Differentiation Potential and Ultrastructure of Endogenous Lung Mesenchymal Stromal Cells; 2016 May. (E-PAS2016:3873.662).
|
| Siddiqui SK, Mustafa S, Vasquez M, Werner SL, Seidner SR. Mechanical Ventilation alters the Differentiation Potential and Ultrastructure of Endogenous Lung MSC; 2016 Apr. (Pediatric Academic Societies Meeting April 30-May 3, 2016, Baltimore, MD).
|
| Mustafa S, Siddiqui SK, Vasquez M, Werner SL, Seidner SR. Effect of Mechanical Ventilation and Postnatal Adaptation on Endogenous Premature Lung Mesenchymal Stromal Cells; 2016 Feb. (RegenMed SA Conference February 11-12, 2016, San Antonio, TX).
|
| Siddiqui SK, Mustafa S, Vasquez M, Werner SL, Seidner SR. Mechanical Ventilation alters the Differentiation Potential and Ultrastructure of Endogenous Lung MSC from Late Preterm Rabbit Lung; 2016 Jan. (American Academy of Pediatrics Meeting on Perinatal Research January 6-8, 2016, Indian Wells, CA).
|
| Siddiqui SK, Mustafa SB, Vasquez MM, Seidner SR. Effect of Mechanical Ventilation and Postnatal Adaptation on Mesenchymal Stromal Cells Isolated from Late Preterm Rabbit Lung; 2016 Jan. (Journal of Investigative Medicine).
|
| Hisey JC, Le Saux CJ, Vasquez MM, Anzueto DG, Seidner SR, Summers PK, Mustafa SB. Abnormal Alveolarization, Surfactant Protein Expression and Lung Function in Caveolin-1-Deficient Newborn Mice; 2013 May. (E-PAS2013:1670.3).
|
| Sorrell MW, McGill L, Johnson-Pais T, Seidner SR, DeFronzo R, Musi N,Blanco CL. Peripheral Insulin Resistance and Impaired Insulin Signaling Contribute to Abnormal Glucose Metabolism in Prematurity; 2013 May. (Pediatric Research E-PAS2013:4170.8).
|
| Blanco CL, Seidner SR, Gastaldelli A, Johnson M, McCurnin DC, Johnson-Pais TL, DeFronzo M, McGill L. Glucose Metabolism in Prematurity: Evidence of Hepatic Insulin Resistance and Molecular Developmental changes in Non-human Primates; 2013 May. (Pediatric Research E-PAS2013:3829.475).
|
| McGill-Vargas, McCurnin D, Seidner S, Nathanielsz P, Blanco CL. Abnormal Aminoacid Profiles in Preterm Non−Human Primates Receiving Parenteral Nutrition; 2013 May. (E-PAS2013:3830.476).
|
| Le Saux CJ, Mustafa, SB, Anzueto, DG, Vasquez, M, Seidner, SR. Deficiency in Caveloin-1 leads to disrupted postnatal alveolarization and abnormal expression of surfactant proteins; 2011 Aug. (Gordon Research Annual Conference, Lung Development, Injury).
|
Journal Article |
| Blanco CL, Mcgill-Vargas LL, Gastaldelli A, Seidner SR, McCurinin DC, Leland MM, Anzueto DG, Johnson MC, Liang H, DeFronzo RA, Musi N. Peripheral Insulin Resistance and Impaired Insulin Signaling Contribute To Abnormal Glucose Metabolism in Preterm Baboons Endocrinology 2015 Mar;156(3):813-823.
|
| Mustafa SB, Isaac, Seidner SR, Dixon PS, Henson BM, and DiGeronimo RJ.
Experimental Lung Research. 40(8):380-91, 2014.
. Mechanical stretch induces lung alpha-epithelial Na+ channel expression Experimental Lung Research 2014 Nov;40(8):380-391.
|
| Namachivayam K, Blanco CL, MohanKumar K, Jagadeeswaran R, Vasquez MM, McGill-Vargas L, Garzon SA, Jain SK, Gill RK, Freitag NE, Weikamp JH, Seidner SR, Maheshwari A. Smad7 inhibits autocrine expression of TGF-?2 in intestinal epithelial cells in baboon necrotizing enterocolitis Am J Physiol Gastrointest Liver Physiol 2013 Jan;304(2):G167-180.
|
| Sutherland MR. Yoder BA. McCurnin D. Seidner S. Gubhaju L. Clyman RI. Black MJ. Effects of ibuprofen treatment on the developing preterm baboon kidney Am J Physiol Renal Physiol 2012 May;302(10):F1286-F1292.
|
| Waleh N, Seidner S, McCurnin D, Giavedoni L, Hodara V, Goelz S, Liu BM, Roman C, Clyman RI, Seidner SR. Anatomic Closure of the Premature Patent Ductus Arteriosus: The Role of CD14+/CD163+ Mononuclear Cells and Vascular Endothelial Growth Factor (VEGF) in Neointimal Mound Formation Pediatr Res 2011 Oct;70(4):332-338.
|
| Jupelli M, Murthy AK, Chaganty BK, Guentzel MN, Selby DM, Vasquez MM, Mustafa SB, Henson BM, Seidner SR, Zhong G, Arulanandam BP. Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life Lab Invest 2011 Oct;91:1530-1539.
|
