Levine, Deborah JoSchool of Medicine |
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Professor of Medicine in Pulmonary and Critical Care Medicine
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| 9/2016 - Present | Professor of Medicine and Cardiothoracic Surgery and Medical Director of Lung Transplantation, Director of Pulmonary Hypertension Center | University of Texas Health Science Center, Medicine, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 2003 | Clinical Fellowship | Lung Transplantation/Interventional Pulmonology | UTHSCSA San Antonio , TX |
| 2002 | Clinical Fellowship | Critical Care Medicine | UTHSCSA San Antonio , TX |
| 2001 | Clinical Fellowship | Pulmonary Disease | Good Samaritan/VAMC Phoenix , AZ |
| 1999 | Internship | Internal Medicine | University of Arizona/Banner/VAMC Phoenix , AZ |
| 1996 | MD | Medicine | University of Arizona College of Medicine Tucson , AZ |
| 1992 | MS | Pharmacology/Toxicology | University of Arizona/College of Medicine Tucson , AZ |
| 1991 | BS | Physiology | University of California Davis , CA |
Antibody Mediated Rejection - Lung Transplantation |
Critical Care Medicine- Critical Care Board certification and practice in the medical intensive care unit, transplant intensive care unit and surgical intensive care unit |
End-stage Lung Disease- (PH, IPF, ILD, CF) |
Internal Medicine- Boarded in internal medicine |
Interventional Pulmonology- Completed fellowship in interventional pulmonology including 2 week course in Heidelberg Germany |
Lung Transplantation- Lung transplant pulmonologist. Care for all aspects of lung transplant patient: ICU care, donor management, post-lung transplant care in and out of the hospital. |
Organ Donor Management in the ICU- Manage organ donors in the icu prior to procurement. This improves the number of donor numbers so we have increased donor organs for transplant recipients. |
Pulmonary Disease- Pulmonologist involved in clinical, research and teaching at UTHSCSA. |
Pulmonary Hypertension- Medical Director of Pulmonary Hypertension Center: Center has >200 patients I follow regularly. This center is the only one in South Texas and the third biggest center in Texas. |
Abstract |
| 1. Michaels M, Plucinski B, Ward E, Strasfeld L, Malinis M, Ho CS, Danziger-Isakov L, Bucio J, Berry G, Rana M, Marboe C, Aslam S, Razonable R, Pouch S, Marklin G, Levitsky J, Levine D, Agarwal A, R La Hoz. Donor Derived Transmissions 2018: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC) Philadelphia: American Transplant Congress 2020; 2020 May. (American Transplant Congress; vol. 165). |
| Riera J, Maldonado C, Mazo C, Martinez M, Baldira J, Lagunes L, Augustin S, Roman A, Due M, Rello J, Levine DJ. Prone positioning as a bridge to recovery from refractory hypoxaemia following lung transplantation; 2017 Aug. (Interact Cardiovasc Thorac Surg). |
| Reinsmoen NL, Mirocha J, Ensor CR,, Marrari M, Chaux G, Levine DJ, Zhang X, Zeevi A. A 3-Center Study Reveals New Insights Into the Impact of Non-HLA Antibodies on Lung Transplantation Outcome; 2017 Jun. (Transplantation). |
| Zamanian RT, Levine DJ, Bourge RC, De Souza SA, Rosenzweig EB, Alnuaimat H, Burger C, Mathai SC, Leedom N, DeAngelis K, Lim A, De Marco T. An observational study of inhaled-treprostinil respiratory-related safety in patients with pulmonary arterial hypertension; 2016 Sep. (Pulmonary Circ). |
| Levine DJ, Glanville AR, Aboyoun C, Belperio J, Benden C, Berry GJ, Hachem R, Hayes D Jr,, Neil D, Reinsmoen NL, Snyder LD, Sweet S, Tyan D,, Verleden G, Westall G, Yusen RD, Zamora M, Zeevi A. Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation; 2016 Apr. (J Heart Lung Transplant). |
| Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O'Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP. Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Donor Management Task Force. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of; 2015 Jun. (Crit Care Med). |
Book Chapter |
| Moot, Rebecca, Attridge, Rebecca, Levine DJ. Pulmonary Arterial Hypertension 8th ed. In: Dipiro, Talbert, Yee, Matzke, Wells and Posey. Pharmacotherapy: A Pathophysiologic Approach. New York, NY: McGraw Hill Medical; 2018. p. 497-511. |
Journal Article |
| Levine DJ. Evaluating Resilience as a Predictor of Outcomes in Lung Transplant Candidates Clinical Transplantation 2020 Oct;. |
| Pennington KM, Benzo RP, Schneekloth TD, Budev M, Chandrashekaran S, Erasmus DB, Lease ED, Levine DJ, Thompson K, Stevens E, Novotny PJ, Kennedy CC. Impact of Affect on Lung Transplant Candidate Outcomes Progress in Transplant 2020 Mar;. |
| Halloran K, Parkes MD, Timofte IL, Snell GI, Westall GP, Hachem R, Kreisel D, Levine D, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Hirji A, Weinkauf J, Halloran PF. Molecular phenotyping of rejection-related changes in mucosal biopsies from lung transplants American Journal of Transplantation 2019 Nov;. |
| Calabrese F, Hirschi S, Neil D, Montero-Fernandez A, Timens W, Verbeken E, Chenard MP, Ivanovic M, Le Pavec J, Pena T, Dorfmuller P, Roux A, Rice A, Perissinotto E, Lunardi F, Levine DJ, Cozzi E, Goddard M. Alveolar Septal Widening as an "Alert" Signal to Look Into Lung Antibody-mediated Rejection: A Multicenter Pilot Study Journal of Transplantation 2019 Nov;103(11):2440-2447. |
| Law N, Hamandi B, Fegbeutel C, Silveira FP, Verschuuren EA, Ussetti P, Chin-Hong PV, Sole A, Holmes-Liew CL, Billaud EM, Grossi PA, Manuel O, Levine DJ, Barbers RG, Hadjiliadis D, Younus M, Aram J, Chaparro C, Singer LG, Husain S. Lack of association of Aspergillus colonization with the development of bronchiolitis obliterans syndrome in lung transplant recipients: An international cohort study Journal of Heart and Lung Transplantation 2019 Sep;38(9):963-971. |
| Klinger JR, Elliott G, Levine DJ, Bossone E, Duvall L, Fagan K, Frantsve-Hawley J, Kawut SM, Ryan JJ, Rosenzweig EB, Sederstrom N, Steen VD, Badesch DB. Response CHEST 2019 Jul;156(1):187-188. |
| Glanville AR, Verleden GM, Todd JL, Benden C, Calabrese F, Gottlieb J, Hachem RR, Levine D, Meloni F, Palmer SM, Roman A, Sato M, Singer LG, Tokman S, Verleden SE, von der Thusen J, Vos R, Snell G. Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT Journal of Heart and Lung Transplantation 2019 May;38(5):483-492. |
| Klinger JR, Elliot CG, Levine DJ, Bossone E, Duvall L, Fagan K, Frantsve-Hawley J, Kawut SM, Ryan JJ, Rosenzweig EB, Sederstrom N, Steen VD, Badesch DB. Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report CHEST 2019 Mar;155(3):565-586. |
| Roux A, Levine DJ, Zeevi A, Hachem R, Halloran K, Halloran PF, Gibault L, Taupin JL, Neil DAH, Loupy A, Adam BA, Mengel M, Hwang DM, Calabrese F, Berry G, Pavlisko EN. Banff Lung Report: Current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody-mediated rejection (AMR) American Journal of Transplantation 2019 Jan;19(1):21-31. |
| Levine DJ, McDonald RJ, Kressel HY. Gadolinium Retention After Contrast-Enhanced MRI Journal of the American Medical Association 2018 Nov;320(18):1853-1854. |
| Aguilar CA, Hamandi B, Fegbeutel C, Silveira FP, Verschuuren EA, Ussetti P, Chin-Hong PV, Sole A, Holmes-Liew C, Billaud EM, Grossi PA, Manuel O, Levine DJ, Barbers RG, Hadjiliadis D, Singer LG, Husain S. Clinical risk factors for invasive aspergillosis in lung transplant recipients: Results of an international cohort study Journal of Heart and Lung Transplantation 2018 Oct;37(10). |
| Hachem RR, Kamoun M, Budev MM, Askar M, Ahya VN, Lee JC, Levine DJ, Pollack MS, Dhillon GS, Weill D, Schechtman KB, Leard LE, Golden JA, Baxter-Lowe L, Mohanakumar T, Tyan DB, Yusen RD. Human leukocyte antigens antibodies after lung transplantation: Primary results of the HALT study American Journal of Transplantation 2018 Sep;18(9):2285-2294. |
| Tambur AR, Campbell P, Claas FH, Feng S, Gebel HM, Jackson AM, Mannon RB, Reed EF, Tinckam K, Askar M, Chandraker A, Chang PP, Colvin M, Demetris AJ, Diamond JM, Dipchand AI, Fairchild RL, Ford ML, Friedewald J, Gill RG, Glotz D, Goldberg H, Hachem R, Knechtle S, Kobashigawa J, Levine DJ, Levitsky J, Mengel M, Milford E, Newell KA, O`Leary JG, Palmer S, Randhawa P, Smith J, Snyder L, Starling RC, Sweet S, Taner T, Taylor CJ, Woodle S, Zeevi A, Nickerson P. Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report American Journal of Transplantation 2018 Jul;18(7):1604-1614. |
| Hamandi B, Fegbeutel C, Silveira FP, Verschuuren EA, Younus M, Mo J, Yan J, Ussetti P, Chin-Hong PV, Sole A, Holmes-Liew CL, Billaud EM, Grossi PA, Manuel O, Levine DJ, Barbers RG, Hadjiliadis D, Aram J, Singer LG, Husain S. Voriconazole and squamous cell carcinoma after lung transplantation: A multicenter study American Journal of Transplantation 2018 Jan;18(1):113-124. |
| Levine DJ, Gonzalez MI, Legendre CM, Runčevski T, Oktawiec J, Colwell KA, Long JR. Calcium Coordination Solids for pH-Triggered Release of Olsalazine ChemMed 2017 Nov;12(21):1739-1742. |
| Milross L, Hachem R, Levine D, Glanville AR. Lung autoantibodies: Ready for prime time? Journal of Heart and Lung Transplantation 2017 Nov;. |
| Palacio F, Reyes, Luis F, Levine DJ, Sanchez, Juan F, Angel LF, Fernandez, Juan F, Levine SM, Rello, Jordi, Abedi A, Restrepo MI. Understanding the concept of health care associated pneumonia (HCAP) in lung transplant recipients CHEST 2015 Aug;148(2):516-522. |
| Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel LF, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O`Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement Crit Care Med 2015 Jun;43(6):1291-1325. |
| Levine DJ, Stohr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR. Mechanism of scrapie prion precipitation with phosphotungstate anions American Chemical Society 2015 May;10(5):1269-1277. |
| Levine DJ. Diagnosis and Management of Pulmonary Arterial Hypertension: Implications for Respiratory Care Respiratory Care 2006 Apr;51(4):368-381. |
| Grasseschi RM, Ramaswamy RB, Levine DJ, Klaassen CD, Wesselius LJ. Cadmium accumulation and detoxification by alveolar macrophages of cigarette smokers Chest 2003 Nov;124(5):1924-1928. |
| Aposhian HV, Levine DJ, Rivera M, Fernando Q. Determination and metabolism of dithiol chelating agents: the zinc chelate of the dimethyl ester of meso-2,3-dimercaptosuccinic acid increase biliary excretion of cadmium and platinum American Chemical Society 1993 Mar;6(2):208-214. |
Not Specified |
| Levine DJ, Al‐Adra DP, Hammel L, Roberts J, Woodle ES, Mandelbrot D, Verna E, Locke J, D'Cunha J, Farr M, Sawinski D, Agarwal PK, Plichta J, Pruthi S, Farr D, Carvajal R, Walker J, Zwald F, Habermann T, Gertz M, Bierman P, Dizon DS, Langstraat C, Al‐Qaoud T, Eggener S, Richgels JP, Chang GJ, Geltzeiler C, Sapisochin G, Ricciardi R, Krupnick AS, Kennedy C, Mohindra N, Foley DP, Watt KD. Pre-Existing Melanoma and Hematological Malignancies, Prognosis and Timing to Solid Organ Transplantation: A Consensus Expert Opinion Statement American Journal of Transplantation 2020 Sep;. |
Private |
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| Funding Agency | |
| Title | The role of C4D staining and donor specific antibodies in Lung Transplant Rejection: A Retrospective Chart Review to evaluate the role of C4D staining and histologic featurers of transplant trans-bronchial biopsies. |
| Status | Active |
| Period | 5/2008 - Present |
| Role | Principal Investigator |
| Grant Detail | |
| Funding Agency | Emphasys, Inc. |
| Title | Endobronchial Valve for Emphysema Palliation Trial - VENT |
| Status | Active |
| Period | 6/2008 - Present |
| Role | Co-Investigator |
| Grant Detail | Goal: To relieve symptoms and improve quality of life of emphysema patients without surgical intervention Evaluate the safety and efficacy of the Emphasys Endobronchial Valve for Emphysema Palliation Trial (VENT) |
| Funding Agency | United Therapeutics |
| Title | ASPIRE: PAH study - A postmarketing observational study to assess respiratory tract adverse events in pulmonary arterial hypertension pstients treated with Tyvaso (Treprostinil) inhalation solution |
| Status | Active |
| Period | 5/2011 - 1/2029 |
| Role | Co-Principal Investigator |
| Grant Detail | PAH study - A postmarketing observational study to assess respiratory tract adverse events in pulmonary arterial hypertension pstients treated with Tyvaso (Treprostinil) inhalation solution |
| Funding Agency | Spiration Inc. |
| Title | A prospective randomized controlled multicenter clinical trial to evaluate the safety and effectiveness of the IBV valve system for the treatment of severe emphysema. |
| Status | Active |
| Period | 7/2005 - 1/2029 |
| Role | Co-Investigator |
| Grant Detail | |
| Funding Agency | Co Therix Inc |
| Title | Registry to EValuate Early and Long-term Pulmonary Arterial Hypertension Disease Management (REVEAL Registry) |
| Status | Active |
| Period | 11/2010 - 1/2019 |
| Role | Principal Investigator |
| Grant Detail | Total funding amount and receipt dependent on participant enrollment. Approved for up to $187,500. Patients are enrolled and updates are done on a quarterly basis for 5 years. There is an annual meeting nationally for centers involved in this area. |
| Funding Agency | UHN Toronto |
| Title | A Multicenter, Multinational, Retrospective Review of Voriconazole Experience for the Prophylaxis against Invasive Aspergillosis in Lung Transplant Recipients |
| Status | Active |
| Period | 10/2012 - Present |
| Role | Principal Investigator |
| Grant Detail | |