Davis, Michael DuffSchool of Medicine |
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Married with 3 children. |
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| 1/2009 - Present | Graduate Research Faculty, Department of Radiology | University of Texas Health Science Center, Radiology, San Antonio, TX |
| 1/2007 - Present | Affiliate Scientist | Southwest National Primate Research Center, San Antonio, TX |
| 4/2005 - Present | Associate Professor and Chief, Animal Imaging Division | UTHSCSA, Research Imaging Ctr, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1987 | Postdoctoral Fellowship | Neuropharmacology | Duke University Durham , NC |
| 1985 | PhD | Pharmacology | University of Zurich Zurich , Switzerland |
| 1982 | MS | Zoology | University of Washington Seattle , WA |
| 1977 | BA | Physiological Psychology/Cell Dev. Biology | University of Arizona Tucson , AZ |
Behavioral Testing- Rodent and non-human primate behavioral testing |
Cortical Impact- Controlled cortical impact (traumatic brain injury) model. |
HPLC Separatrions- HPLC separations with fluorometric and electrochemical detection. |
Immunohistochemistry |
In Vivo Intracerebral microdialysis- Microdialysis in anesthetized and awake animals including rodents and non-human primates. |
In vivo and vitro electrophysiology- In vivo and in vitro single unit electrophysiology |
Intrcerebral fluorescence monitoring- In vivo intracerebral fluorescence monitoring using molecular probes in anesthetized and awake rodents and non-human primates. |
Molecular Neurobiology- Molecular neurobiology (western blots, immunohistochemistry, in situ hybridization) |
Neuroendocrine models- Various neuroendocrine models (bioassay, RIA) |
Parkinson''s Disease Research- Mouse MPTP model of Parkinson''s Disease |
Positron Emission Tomography (PET/ Micro-PET)- PET (Micro PET) in vivo imaging (FDG, receptor occupancy) |
Journal Article |
| Okeson DM, Coke RL, Kochunov P, Davis MD. Magnetic resonance imaging findings in a red kangaroo (Macropus rufus) with otitis J Zoo Wildl Med 2008 Dec;39(4):667-670. |
| Szab CA, Narayana S, Franklin C, Knape KD, Davis MD, Fox PT, Leland MM, Williams JT. "Resting" CBF in the epileptic baboon: correlation with ketamine dose and interictal epileptic discharges Epilepsy Res 2008 Nov;82(1):57-63. |
| Arar NH, Freedman BI, Adler SG, Iyengar SK, Chew EY, Davis MD, Satko SG, Bowden DW, Duggirala R, Elston RC, Guo X, Hanson RL, Igo RP, Ipp E, Kimmel PL, Knowler WC, Molineros J, Nelson RG, Pahl MV, Quade SR, Rasooly RS, Rotter JI, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Zager PG, Abboud HE. Heritability of the severity of diabetic retinopathy: the FIND-Eye study Invest Ophthalmol Vis Sci 2008 Sep;49(9):3839-3845. |
| Lee, K., P.T. Fox, S.H. Lee, J.L. Lancaster, P.A. Jerabek and M.D. Davis. A positron-probe for arterial input function quantification: implementation and H215O PET validation J. IEEE 2008 Jan;:1-6. |
| Bao, A., B. Goins, G.D. Dodd III, A. Soundararajan, C. Santoyo, R.A. Otto, M.D. Davis and W.T.Phillips. Real-time iterative monitoring of radiofrequency ablation tumor therapy with 15O-water PET imaging J. Nuclear Medicine 2008 Jan;49:1723-1729. |
| Brammer, D.W., J.M. Riley, S.C. Kreuser, K.R. Zasadny, M.J. Callahan and M.D. Davis. Harderian gland adenectomy: a method to eliminate confounding radio-opacity in assessment of the rat brain metabolism by 18F-FDG microPET imaging J. American Assoc. Laboratory Animal Science, (in press) 2008 Jan;. |
| Bahadur AN, Wu IQ, Weinstein DM, Davis MD, Lewis DA, Kochunov P, Keller C. Multimodality Chamber for coregistered anatomical and molecular imaging of small animals [Cover Article] Lab Animal 2007 Sep;36(8):29-35. |
| Szab CA, Narayana S, Kochunov PV, Franklin C, Knape K, Davis MD, Fox PT, Leland MM, Williams JT, Fox, PT. PET imaging in the photosensitive baboon: case-controlled study Epilepsia 2007 Feb;48(2):245-253. |
| Kumar AP, Bhaskaran S, Ganapathy M, Crosby K, Davis MD, Kochunov P, Schoolfield J, Yeh IT, Troyer DA, Ghosh R, Yeh I. Akt/cAMP-Responsive Element Binding Protein/Cyclin D1 Network: A Novel Target for Prostate Cancer Inhibition in Transgenic Adenocarcinoma of Mouse Prostate Model Mediated by Nexrutine, a Phellodendron Amurense Bark Extract Clin Cancer Res 2007 Jan;13(9):2784-2794. |
| Kumar, P., R. Gosh, M. Ganapathy, J.D. Schoolfield, I.T. Yeh, D.A. Troyer, P. Kochunov, M.D. Davis. Akt/CREB/Cyclin D1 network: novel target for prostate cancer inhibition mediated by Nexrutine, a Phellodendron amurense bark extract (in press) Clinical Cancer Research 2007 Jan;13(9):2784-2794. |
| Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC. Calcium channel alpha(2)-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: An ex vivo autoradiographic study in alpha(2)-delta type 1 genetically modified mice Brain Res 2006 Feb;. |
| Petrie KA, Bubser M, Casey CD, Davis MD, Roth BL, Deutch AY. The neurotensin agonist PD149163 increases Fos expression in the prefrontal cortex of the rat Neuropsychopharmacology 2004 Oct;29(10):1878-1888. |
Federal |
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| Funding Agency | DOD |
| Title | STRONGSTAR Neuroimaging Core |
| Status | Active |
| Period | 9/2008 - 8/2013 |
| Role | Contributor |
| Grant Detail | This is the NeuroImaging Core for the STRONGSTAR Multidisciplinary PTSD Research Consortium. |
| Funding Agency | NIH/NCRR |
| Title | A Neuroimaging Study of Primate Brain Development and Aging in the Marmoset |
| Status | Active |
| Period | 9/2007 - 6/2012 |
| Role | Principal Investigator |
| Grant Detail | The overall goal of this project is evaluate neonatal, juvenile, adult and aged marmoset groups in 3 specific aims. |
| Funding Agency | NIH/NIDDKD |
| Title | The Common Marmoset as a Primate Model of Maternal Obesity |
| Status | Active |
| Period | 9/2006 - 9/2010 |
| Role | Co-Investigator |
| Grant Detail | Given their small size, high fertility and short life span, common marmosets are an efficient nonhuman primate model in which to examine the effects of early life environment on adult disease outcomes. The goal of this proposed research is to determine the extent to which maternal propensity to obesity predisposes offspring to disorders of glucose regulation and weight homeostasis in this species. |
| Funding Agency | NIH |
| Title | Delay discounting and fMRI in rhesus monkeys |
| Status | Active |
| Period | 5/2008 - 4/2010 |
| Role | Co-Investigator |
| Grant Detail | Studies in this application will develop a delay discounting procedure in non-human primates that will be compatible with brain imaging. Collectively, these developmental studies (R21) will provide the foundation for a future R01 application that will investigate the neural substrates underlying delay discounting and how these substrates are affected by drugs of abuse. |
| Funding Agency | NIH/NCRR |
| Title | A High-Field (7T) MRI System for Translational Imaging Research in San Antonio |
| Status | Active |
| Period | 5/2007 - 4/2009 |
| Role | Principal Investigator |
| Grant Detail | This new MRI will drive high-caliber translatable research directed at improving our understanding and treatment of human diseases, provide an important training environment, and since its use involves survivable testing, at lesser sacrifice of animal subjects. |
| Funding Agency | NIH/NCRR |
| Title | High Resolution Large-Bore MicroPET System for Translational Imaging Research |
| Status | Complete |
| Period | 12/2007 - 11/2008 |
| Role | Principal Investigator |
| Grant Detail | This PET system will enhance our ability to image, non-destructively, both animal and human organ systems alike for biomedical research and the evaluation of potential treatment strategies in cancer, age-related disorders and other medical needs. |
Private |
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| Funding Agency | URC/UTHSCSA |
| Title | Development of a Transient and Permanent Rat Stroke Model as Assessed with Non-Invasive PET and MRI Imaging |
| Status | Complete |
| Period | 7/2007 - 6/2008 |
| Role | Principal Investigator |
| Grant Detail | |