Abstract |
| Suleman S. Hussain, Paul Rivas, Roble Bedolla, Nikos Papanikolaou, Robert L. Reddick, Brad H. Pollock, Daniel C. Chan, Rita Ghosh and Addanki P. Kumar. Downregulation of ribosomal protein rpS6 overcomes radioresistance in prostate cancer; 2015 Apr. (Proceedings of American Association for Cancer Research).
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Dissertation/Thesis |
| Divya Chakravarthy. Palmatine in pancreatic stellate cell and cancer cell interaction 2015. |
| Izhar Singh Batth. New roles for RON in prostate cancer 2014. |
Journal Article |
| Kumar AP. Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model PLOS ONE:1-8.
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| Thapa D, Huang SB, Munoz AR, Yang X, Bedolla R, Hung CN, Chen CL, Huang TH, Liss MA, Reddick RL, Miyamoto, H, Kumar AP and Ghosh R. Attenuation of NADPH: Quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFb signaling Communications Biology 2020 Feb;3:12-22.
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| Kumar AP. Receptor tyrosine kinase RON as predictive marker for aggressive prostate cancer in African Americans Molecular Carcinogenesis 2019 Mar;:1-8.
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| Meng P, Bedolla RG, Yun H, Fitzpatrick JE, Kumar AP and Ghosh R. CONTEXTUAL ROLE OF E2F1 in suppression of melanoma cell motility and invasion Molecular Carcinogenesis 2018 Dec;58:1701-1710.
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| Kumar AP. Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation Cancer Letters 2018 Oct;433:232-241.
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| Kumar AP. BRCA1 interacting protein COBRA1 facilitates adaptation to castrate resistant growth conditions International Journal of Molecular Sciences 2018 Jul;19(7):1-12.
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| Kumar AP, D Chakravarthy, A Munoz, A Su, RF Hwang, BR Keppler, DE Chan, G Halff, R Ghosh. Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1 Cancer Letters 2018 Apr;419:103-115.
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| Kumar AP. Single cell RNA Seq reveal subpopulation of prostate cancer cells Cancer Research 2018 Feb;78:853-864.
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| Zhang Y, Li L, Wang J, Cheng W, Zhang J, Li X, Zhang Z, Gong J, Ghosh R, Kumar AP, Xie J. Combination of Nexrutine and Docetaxel suppresses NFκB-mediated activation of c-FLIP MOLECULAR CARCINOGENESIS 2017 May;.
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| Zhao S, Chen C, Chang K, Karnad A, Jagirdar J, Kumar AP, Freeman JW. CD44 Expression Level and Isoform Contributes to Pancreatic Cancer Cell Plasticity, Invasiveness, and Response to Therapy Clinical Cancer Research 2016 Nov;22:5592-5604.
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| Huang G, Osmulski PA, Bouamar H, Mahalingam D, Lin CL, Liss MA, Kumar AP, Chen
CL, Thompson IM, Sun LZ, Gaczynska ME, Huang TH. TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts Oncotarget 2016 Nov;7(47):77124-77137.
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| Batth, IS., Yun, H., Meng, P., Osmulski, P., Huang, TH., Bedolla, R., Reddick, RE., Kumar AP. Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer Oncotarget 2016 Jan;.
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| Hambright HG, Meng, P, Kumar AP and Ghosh R. Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells. Oncotarget (in press) Oncotarget 2015 Jan;.
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| Yun, HY., Xie, J., Olumi, AF., Ghosh, R., Kumar AP. Activation of AKR1C1/ERB induces apoptosis by downregulation of c-FLIP in prostate cancer cells: A prospective therapeutic opportunity Oncotarget 2015 Jan;.
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| Swanson, GP., Jones WE., Ha, CS., Jenkins, CA., Kumar AP and Basler, J. Tolerances of Phellodendron amurense bark extract (Nexrutine) in human prostate cancer patients. Phytotherapy Research doi: 10.1002/ptr. 5221. [Epub ahead of print] PMID:25205619 Phytotherapy Research 2015 Jan;.
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| Thapa D, Meng P, Bedolla RG, Reddick RL, Kumar AP AND Ghosh R. NQO1 suppresses NF-kB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis Cancer Research 2014 Jan;74(5644):5644-5655.
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| Kumar AP. Combined targeting of Stat3/NF B/Cox-2/EP4 for effective management of pancreatic cancer Clinical Cancer Research 2014 Jan;20.
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| Kumar AP. Palmatine suppresses rpS6/NFκB/FLIP to inhibit growth and invasion in androgen independent prostate cancer cells Molecular Carcinogenesis 2014 Jan;.
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| Gong, JJ., Xie, J., Bedolla, R., Rivas, P., Chakravarthy, D. Freeman, JW., Reddick, R., Kopetz, S., Peterson, A., Wang, H., Fischer, SM and Kumar AP. Combined targeting of Stat3/NFkB/Cox-2/EP4 for effective management of pancreatic cancer Clinical Cancer Research (in press;doi:10.1158/1078-0432.CCR-13-1664);Selected as on of the highlights of the issue 2014 Jan;.
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Not Specified |
| 5. Patel DP, Abuchowski K, Bedolla R, Rivas P, Musi N, Reddick R and Kumar AP. Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model PLOS ONE 2020 Feb;14:1-8.
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Review Article |
| Halff G, Amanda r. Munoz, Divya Chakravarthy, Jingjing Gong, Rita Ghosh, Addanki P. Kumar. Pancreatic Cancer: Current Status and Challenges Current Pharmacology Reports 2017 Oct;3:396-408.
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| SS Hussain, APKumar and R Ghosh. Food based natural products for cancer management: Is the whole greater than the sum of the parts? Seminars in Cancer Biology 2016 Aug;.
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| Hussain, SS., Patel, D., Ghosh, R and Kumar AP. Extracting the Benefit of Nexrutine? for Cancer Prevention Curr Pharmacol Rep 2015 Dec;:365-372.
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| Kumar AP. Recepteur d'origine nantais (RON), more than a kinase: Role in castrate-resistant prostate cancer Molecular Carcinogenesis 2015 Oct;.
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| Mukherjee,N., Kumar AP and Ghosh R. DNA Methylation and Flavonoids in Genitourinary Cancers Curr Pharmacol Rep 2015 Apr;:112-120.
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| Gong, JJ., Kumar,S., Graham, G, and Kumar, AP. FLIP: Molecular switch between apoptosis and necroptosis Molecular Carcinogenesis (in perspective, DOI 10.1002/MC.22027) 2013 Jan;.
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