UTHSCSA Faculty Profiles v1.0
Lei, Xiufen
School of Medicine
Pediatrics
(210) 562-9044
lei@uthscsa.edu
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| 12/2005 - Present |
Instructor/Research |
UTHSCSA, Pediatrics, San Antonio, TX |
| Year |
Degree |
Discipline |
Institution |
| 1994 |
PhD |
Epidemiology |
Beijing Medical University
China |
| 1991 |
MS |
Environmental Health |
Shanxi Medical University
China |
| 1988 |
MD |
Preventive Medicine |
Shanxi Medical University
China |
Lab Experience -
Evaluation of experimental results and troubleshooting |
Lab Experience -
Actively attending related research seminars |
Lab Experience -
Independently designing and establishing experiment |
Lab Experience -
Training students and research assistants |
Lab Techniques -
Mice bone marrow cell chromosome analysis, nude mice xenograft model system |
Lab Techniques -
Vector NTI software, Subcloning, DNA & RNA extraction, plasmid DNA preparation, M13 phage DNA preparation, single strand DNA preparation, siRNA transfection |
Lab Techniques -
Immunocytochemistry, immunohistochemistry, fluorescent microscope |
Lab Techniques -
Hybridoma technique and monoclonal antibodies |
Lab Techniques -
Cell cycle analysis (flowcytometry), cell apoptosis detection (AnnexinV-FITC staining, Cell death detection ELISA assay, WB of Caspase or PARP) |
Lab Techniques -
Western blot, immunoprecipitation, chromatin immunoprecipitation (ChIP) assay |
Lab Techniques -
PCR, site-directed mutagenesis PCR, RT-PCR, real-time PCR, PCR-SSCP. |
Lab Techniques -
Cell culture, cell transfection, cell retrovirus infection, cell proliferation assay, call migration and invasion assay, soft agarose assay, reporter gene assay (Luciferase assay). |
Journal Article |
| Lei X, Wang L, Yang J, Sun L. TGFβ signaling supports survival and metastasis of endometrial cancer cells Cancer Management and Research 2009 Jan;1:15-24.
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| Lei X, Yang J, Nichols RW, Sun LZ, Sun L. Abrogation of TGF beta signaling induces apoptosis through the modulation of MAP kinase pathways in breast cancer cells Exp Cell Res 2007 May;313(8):1687-1695.
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| Bandyopadhyay A, Agyin JK, Wang L, Tang Y, Lei X, Story BM, Cornell JE, Pollock BH, Mundy GR, Sun L-Z. Inhibition of pulmonary and skeletal metastasis by a TGFβ Type I receptor kinase inhibitor Cancer Res 2006 Jan;66(13):6714-6721.
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Abstract |
| Lei X, Bai Z, Ye F, Zhou F, Gao SJ. Expression and functions of KSHV microRNAs; 2007 Aug. (the 10th international workshop on Kaposi''s Sarcoma associated herpesvirus(KSHV) and related agents).
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| Lei X, Sun L. Estrogen Suppresses the DNA Mismatch Repair Activity in Human Estrogen Receptor Positive Breast Cancer Cells; 2005 Apr. (Proceedings of 96th Annual meeting of American Association for Cancer Research, Anaheim, CA, Abstract #1785).
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| Lei X, Sun L. Estrogen Suppresses the DNA Mismatch Repair Activity in Human Estrogen Receptor Positive Breast Cancer Cells; 2004 Nov. (The 13th Annual Symposium on Cancer Research in San Antonio and South Texas, Abstract #27. First Prize for postdoctoral fellows).
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