Henry, Michael ADental School |
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| 9/2005 - Present | Professor w/tenure | University of Texas Health Science Center San Antonio, Endodontics, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1992 | Postdoctoral Fellowship | Department of Neurological Surgery | University of Washington Seattle , WA |
| 1992 | Postdoctoral Training | Individual Award from the NIDR | University of Washington Seattle , WA |
| 1991 | PhD | Biological Structure | University of Washington School of Medicine Seattle , WA |
| 1987 | Residency | Univ. of Florida, College of Dentistry Gainesville , FL |
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| 1987 | Postdoctoral Fellowship | Dental Occlusion and Orofacial Pain | University of Florida Gainesville , FL |
| 1985 | Postdoctoral Fellowship | Department of Neurological Surgery | University of Washington, School of Medicine Seattle , WA |
| 1983 | DDS | University of Washington, School of Dentistry Seattle , WA |
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| 1982 | Internship | Department of Neurological Surgery | University of Washington Seattle , WA |
| 1978 | BS | Zoology (Cum Laude) | Washington State University Pullman , WA |
Neuroanatomy, electron/confocal microscopy, pain- 1)The normal organization of the trigeminal brainstem nuclear complex and its response and reorganization following injury with emphasis on central nervous system plasticity. 2)The neuroanatomical basis for pain transmission and modulation within the trigeminal nucleus. 3)The correlation of basic research findings with the pathophysiology of orofacial pain patients and the development of new treatments for these patients. 4)Sodium channel localization within the normal and injured rat trigeminal system; contribution to neuropathic pain states. 5)Sodium channel and thermoreceptor localization within normal and diseased human teeth. 6) Human trigeminal pulpal pain mechanisms. 7) Regeneration of the human dental pulp with post-natal, dentally-derived stem cells. 8) Gial-neuro-immune-vascular interactions in neuropathic and inflammatory trigeminal pain states in humans and rats. |
Journal Article |
| Jeske NA, Patwardhan AM, Henry MA, Milam SB. Fibronectin stimulates TRPV1 translocation in primary sensory neurons J Neurochem 2009 Feb;108(3):591-600. |
| Henry MA, Luo S, Foley BD, Rzasa RS, Johnson LR, Levinson SR. Sodium channel expression and localization at demyelinated sites in painful human dental pulp Journal of Pain 2009 Jan;10(7):750-758. |
| Fehrenbacher JC, Sun XX, Locke EE, Henry MA, Hargreaves KM. Capsaicin-evoked iCGRP release from human dental pulp: A model system for the study of periperhal neuropeptide secretion in normal health tissue Pain 2009 Jan;144:253-261. |
| Khan AA, Diogenes A, Jeske NA, Henry MA, Akopian A, Hargreaves KM. Tumor necrosis factor alpha enhances the sensitivity of rat trigeminal neurons to capsaicin Neuroscience 2008 Aug;155(2):503-509. |
| Jeske N, Diogenes A, Ruparel NB, Fehrenbacher JC, Henry M, Akopian AN, Hargreaves KM. A-Kinase Anchoring Protein Mediates TRPV1 Thermal Hyperalgesia through PKA Phosphorylation of TRPV1 Pain 2008 Mar;138:175-193. |
| Hargreaves KM, Giesler T, Wang Y, Henry MA. Regeneration potential of the young permanent tooth: What does the future hold? Journal of Endodontics 2008 Jan;34:S51-S56. |
| Luo S, Perry GM, Levinson SR, Henry MA. Nav1.7 expression is increased in painful human dental pulp Molecular Pain 2008 Jan;4:16-16. |
| Alvarado L, Perry, G, Hargreaves KM, Henry MA. TRPM8 axonal expression is decreased in painful human teeth with irreversible pulpitis and cold hyperalgesia Journal of Endodontics 2007 Jan;33:1167-1171. |
| Henry MA, Freking AR, Johnson LR, Levinson SR. Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury BMC Neuroscience 2007 Jan;8. |
| Henry MA, Freking AR, Johnson LR, Levinson SR. Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve Pain 2006 Jul;. |
| Henry MA, Rzasa RS, Beeler JJ, Levinson SR. Caspr reveals an aggregation of nodes and flanking node free zones at the rat trigeminal sensory root and dorsal root entry zones GLIA 2005 Feb;49(3):445-450. |
| Henry MA, Sorensen HJ, Johnson LR, Levinson SR. Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp Neurosci Lett 2005 Jan;380(1-2):32-36. |
| Savage MG, Henry MA. Preoperative nonsteroidal anti-inflammatory agents: review of the literature Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004 Aug;98(2):146-152. |
Book Chapter |
| Henry MA, Hargreaves KM. Peripheral mechanisms of odontogenic pain. In: HA Gremillion (Ed). Dental Clinics of North America, Temporomandibular Disorders and Orofacial Pain. Philadelphia, PA: Saunders; 2007. p. 19-44. |
Abstract |
| Trevino EG, Henry MA, Patwardhan AM, Perry, GM, Sun, X, Helesic, G, Locke, E, Hargreaves KM. The effect of different irrigants on SCAP in human roots; 2009 Jan. (J Dent Res; vol. 88). |
| Diogenes AR, Akopian AN, Henry MA, Perry GM, Hargreaves KM. A mechanism for abscess-related pain: How bacteria directly sensitizes trigeminal nociceptors; 2009 Jan. (J Endod; vol. 35, no. 432). |
| Luo S, Perry GM, Levinson SR, Henry MA. Schwann cell proliferation precedes macrophage infiltration following infraorbital nerve injury; 2009 Jan. (J Dent Res; vol. 88). |
| Perry GM, Luo S, Levinson SR, Henry MA. Sodium channel Nav1.6 expression in painful and non-painful human teeth; 2009 Jan. (J Dent Res; vol. 88). |
| Millar GC, Luo S, Perry GM, Hargreaves KM, Henry MA. Immunohistochemical characterization of TRPV1 staining in human dental pulp; 2009 Jan. (J Dent Res; vol. 88). |
| Henry MA, Luo S, Perry GM, Levinson SR. VEGF and Flk-1 expressions increase following infraorbital nerve injury; 2009 Jan. (J Dent Res; vol. 88). |
| Trevino EG, Henry MA, Patwardhan AM, Perry GM, Sun X, Helesic G, Locke E, Hargreaves KM. The effect of different irrigation solutions on the survival of stem cells of the apical papilla (SCAP) in a PRP scaffold in human root tips; 2009 Jan. (J Endod; vol. 35, no. 428). |
| Moridinia M, Gomez R, Ruparel NB, Henry MA, Jeske NA. Biochemical characterization of the ECM protein fibronectin following peripheral inflammation; 2009 Jan. (J Dent Res; vol. 88). |
| Jeske NA, Patwardhan AM, Akopian AN, Scotland PE, Henry MA. A-Kinase anchoring protein 150 mediates protein kinase C-directed phosphorylation and sensitization of TRPV1; 2008 Jan. (IASP). |
| Maggio A, Vela J, Perry GM, Henry MA, Hargreaves KM. B1 adrenergic receptor expression on human dental pulp neurons; 2008 Jan. (J. Dent. Res). |
| Luff KC, Khan A, Perry GM, Henry MA, Hargreaves KM. Tumor necrosis factor receptor I expression in inflamed human pulps; 2008 Jan. (J Dent Res). |
| Scotland PE, Helesic G, Perry G, Henry MA, Hargreaves KM, Akopian AN. Colocalization of prolactin and TRPV1 in inflamed rat hindpaw skin; 2008 Jan. (IASP). |
| Luo S, Perry GM, Helesic G, Levinson SR, Henry MA. Increased expression of sodium channel Nav1.7 in painful human teeth; 2008 Jan. (J Dent Res). |
| Bruggeman JJ, Perry GM, Levinson SR, Henry MA. Nav1.6 sodium channel expression in rat model for trigeminal neuralgia; 2008 Jan. (J Dent Res). |
| Perry GM, Johnson LR, Levinson SR, Henry MA. Glial and immune cell responses following rat infraorbital nerve lesion; 2008 Jan. (J Dent Res; vol. 87). |
| Wood AA, Perry GM, Henry MA. Nerve density in normal and carious/non-painful human dental pulp; 2008 Jan. (J Dent Res). |
| Geisler TM, Wang Y, Perry GM, Henry MA, Sun X, Locke E, Hargreaves KM. Regenerative endodontics: growth factors control the phenotype of human dental pulp stem/progenitor cells; 2008 Jan. (J Endod; vol. 34, no. 341). |
| Scotland PE, Diogenes AR, Jeske NA, Patwardhan AM, Henry MA, Hargreaves KM, Akopian AN. Prolactin sensitizes TRPV1 and produces hyperalgesia in male rats; 2008 Jan. (Society for Neuroscience). |
| Jeske NA, Patwardhan AM, Akopian AN, Henry MA. A-kinase anchoring protein mediates protein kinase C-directed phosphorylation and sensitization of TRPV1; 2008 Jan. (Society for Neuroscience). |
| Rowan, MP, Jeske NA, Henry MA, Milam SB, Berg KA, Clarke WP. Regulation of Mu Opioid receptor signaling in trigeminal ganglion (TG) neurons by RGD-binding integrins Society for Neuroscience, San Diego, CA; 2007 Jan. |
| Stark FW, Perry GM, Johnson LR, Levinson SR, Henry MA. Sodium channel expression in an animal model for trigeminal neuralgia; 2007 Jan. (J. Dent. Res; vol. 86, no. 0703). |
| Scotland PE, Diogenes AR, Sun X, Helesic G, Henry MA, Hargreaves KM. Effect of CFA on peripheral prolactin levels in inflamed tissue; 2007 Jan. (Society for Neuroscience). |
| Ball JS, Hargreaves KM, Henry MA. Co-expression of TLR2 receptor on TRPV1 positive trigeminal nociceptors; 2007 Jan. (J Dent Res; vol. 86). |
| Perry GM, Johnson LR, Levinson SR, Henry MA. Decreased sodium channel expression in sensory neurons after nerve injury; 2007 Jan. (J Dent Res; vol. 86). |
| Henry MA, Perry GM, Johnson LR, Levinson SR. Increased sodium channel expression following long-term infraorbital nerve injury; 2007 Jan. (J Dent Res; vol. 86). |
| Ball JS, Hargreaves KM, Henry MA. Co-expression of TLR2 receptor on TRPV1 positive trigeminal nociceptors; 2007 Jan. (J Dent Res; vol. 86). |
| Alvarado LT, Henry MA, Hargreaves KM, Perry GM. TRPA1 and TRPM8 expressions in normal and cold-sensitive human tooth pulp; 2007 Jan. (J Endod; vol. 33). |
| Jeske NA, Diogenes, A, Ruparel, NB, Fehrenbacher, JC, Henry MA, Akopian AN, Hargreaves KM. PKA Sensitization of TRPV1 is Dependent on A-Kinase Anchoring Protein Keystone TRP Meeting, Boulder, CO; 2007 Jan. |
| Carlson P, Freking AR, Johnson LR, Levinson SR, Henry MA. Rat infraorbital nerve lesion augments sodium channels at distant sites; 2006 Jan. (J Dent Res; vol. 85). |
| Henry MA. Alterations in sodium channels and caspr relationships in painful teeth; 2006 Jan. (J Dent Res; vol. 85). |
| Henry MA. Sodium channel Nav1.6 expression is increased in the rat infraorbital nerve after injury; 2006 Jan. (Journal of Pain; vol. 7, no. 4). |
| Henry MA. Quantitative analysis of sodium channel expression in normal and painful human teeth; 2006 Jan. (Journal of Pain; vol. 7, no. 4). |
| Henry MA, Freking AR, Johson LR, Levinson SR. Rat infraorbital nerve lesion causes altered sodium channel distributions; 2005 Jan. (J Dent Res; vol. 84). |
| Henry MA, Freking AR, Johnson LR, Levinson SR. Quantitative analysis of altered sodium channel distributions following an infraorbital nerve lesion in the rat; 2005 Jan. |
| Sorensen HJ, Skidmore L, Rzasa RS, Kleier DJ, Levinson SR, Henry MA. Comparison of pulpal sodium channel density in normal teeth to diseased teeth with severe spontaneous pain; 2004 Jan. |
| Miller NR, Rzasa RS, Levinson SR, Henry MA. Sodium channel localization in rat infraorbital nerve; 2004 Jan. |
| Henry MA, Rzasa RS, Westrum LE, Levinson SR. Sodium channel Nav1.6 isoform localization in rat trigeminal ganglion; 2004 Jan. (J Dent Res; vol. 83). |
Federal |
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| Funding Agency | NIH- NIDCR |
| Title | Prolactin Regulation of Trigeminal Nociceptors |
| Status | Active |
| Period | 8/2007 - 5/2012 |
| Role | Co-Investigator |
| Grant Detail | |
| Funding Agency | NIDCR |
| Title | Sodium Channel Expression in Human Teeth |
| Status | Active |
| Period | 1/2005 - 12/2009 |
| Role | Principal Investigator |
| Grant Detail | |
| Funding Agency | NIDCR |
| Title | Trigeminal Neuropathic Pain Mechanisms |
| Status | Active |
| Period | 8/2002 - 7/2008 |
| Role | Principal Investigator |
| Grant Detail | |