UTHSCSA Faculty Profiles v1.0

Doiron, Bruno

School of Medicine
(210) 567-0767

As a project leader I have made major discoveries in the field of gene regulation by nutrients and have 2 patents on the modulation of glucose metabolism as it relates to the treatement diabetes and cancer. I have extensive experience in basic research at the physiologic and molecular levels and then application to the biotechnology field. I demonstrated for the first time that in vivo injection of viral vector to suppress Grb10 expression into the adult mouse pancreas induces apoptosis in both exocrine and endocrine tissues. This novel anti-apoptotic function of Grb10 in adult pancreas may help to elucidate the mechanisms which regulate the balance between insulin and glucagon cell mass in the pathogenesis of type 2 diabetes. More recently, I have developed a method in vivo to target specifically adult pancreas with viral vector that will be used in my program of research Cellular Networking Integration Processing (CNIP) to induce beta cell formation in vivo in adult pancreas. In summary, I have demonstrated record of successful and productive research both in industry and in academia.

6/2012 - Present Assistant Professor and Other University of Texas at San Antonio, Biology, San Antonio, TX
7/2007 - Present Assistant Professor UTHSCSA, Medicine, San Antonio, TX