UTHSCSA Faculty Profiles v1.0
Norton, Luke
School of Medicine
Medicine
(210) 567-0739
nortonl@uthscsa.edu
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|
| 1/2014 - Present |
Assistant Professor/Research |
University of Texas Health Science Center at San Antonio, Medicine |
| 4/2010 - Present |
Instructor and Other |
University of Texas Health Science Center San Antonio (UTHSCSA), Medicine, San Antonio, TX |
| Year |
Degree |
Discipline |
Institution |
| 2007 |
PhD |
Biomedical Science (NA) |
University of Nottingham
Nottingham , England |
| 2003 |
BS |
Human Physiology (First class honours) |
University of Hertfordshire
Hatfield , England |
Molecular genetics of type 2 diabetes -
My area of interest lies with the fundamental molecular biology of type 2 diabetes and, more specifically, how genetic variation impacts an individual's risk for the development and progression of the disease. My main goals are to 1) find new genes that are associated with diabetes and 2) characterise the functional role of these genes as it pertains to the development of the diabetes. To this end I employ numerous experimental approaches ranging from in vivo human to detailed in vitro cell culture studies. |
| Date |
Description |
Institution |
# Students |
| 5/2013 - Present |
Ph.D. Dissertations Directed |
UTHSCSA |
|
|
| 5/2013 - Present |
Membership on Supervising Committee |
UTHSCSA |
|
|
Journal Article |
| Norton L
Chen X
Fourcaudot M
Acharya NK
DeFronzo RA
Heikkinen S. The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells Nucleic Acids Research 2014 Dec;42(22).
|
| Tsintzas K, Norton L, Chokkalingam K, Nizamani N, Cooper S, Stephens F, Billeter R, Bennett A. Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle Clinical Science 2013 Jun;.
|
| Kanat M, Mari A, Norton L, Winnier D, DeFronzo RA, Jenkinson CP and Abdul-Ghani MA. Distinct Beta Cell Defects in Impaired Fasting Glucose and Impaired Glucose Tolerance Diabetes 2012 Feb;.
|
Review Article |
| Abdul-Ghani MA, Norton L, DeFronzo RA. The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia Diabetes Obes Metab 2012 Jan;14:5-14.
|
Private |
| Funding Agency |
Metabolic Solutions Devlopment Agency |
| Title |
Efficacy and mechanism of action of anti-diabetic drug MSDC-0602 |
| Status |
Active |
| Period |
2/2013 - Present |
| Role |
Co-Investigator |
| Grant Detail |
|
| Funding Agency |
|
| Title |
Sodium Coupled Glucose Transporter (SGLT) Expression in the Human Diabetic Kidney |
| Status |
Active |
| Period |
3/2010 - Present |
| Role |
Co-Principal Investigator |
| Grant Detail |
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