Meng, XiangzhiGraduate School of Biomedical Sciences |
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| 12/2006 - Present | Research Scientist | University of Texas Health Science Center at San Antonio, Microbiology, Immunology, and Molecular Genetics, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 2003 | PhD | Virology | National Institute for Viral Disease Control and Prevention, Chinese CDC Beijing , China |
| 2000 | MS | Microbiology | Suzhou Medical College Suzhou , China |
| 1992 | MD | Clinical Medicine | Jining Medical College Jining , China |
| Postdoctoral Training | Virology | National Institute for Viral Disease Control and Prevention Beijing , China |
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| Postdoctoral Training | Virology | University of Texas Health Science Center at San Antonio SAN ANTONIO , TX |
Book Chapter |
| Meng X, Rose L, Xiang Y. Interferon antagonisms by poxviruses. In: Edited by Suryaprakash Sambhara and Takashi Fujita. Nucleic Acid Sensors and Antiviral Immunity. Austin, TX: Landes Bioscience; 2012. |
Journal Article |
| Thomas Kaever, Michael H. Matho, Xiangzhi Meng, Lindsay Crickard, Andrew Schlossman, Yan Xiang, Shane Crotty, Bjoern Peters and Dirk M. Zajonc. Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox Journal of Virology 2016 Apr;90(9):4334-4345. |
| Meng X, Krumm B, Li Y, Deng J, Xiang Y. Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins Proc Natl Acad Sci USA 2015 Nov;. |
| Matho MH, Schlossman A, Meng X, Benhnia MR, Kaever T, Buller M, Doronin K, Parker S, Peters B, Crotty S, Xiang Y, Zajonc DM. Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer PLoS Pathog 2015 Sep;11(9):1005148-1005148. |
| Krumm B, Meng X, Xiang Y, Deng J. Crystallization of interleukin-18 for structure-based inhibitor design Acta Crystallogr F Struct Biol Commun 2015 Jun;71:710-717. |
| Kolli S, Meng X, Wu X, Shengjuler D, Cameron CE, Xiang Y*, Deng J*. (*co-corresponding author). Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication Journal of Virology 2015 Feb;89(4):2209-2219. |
| Matho MH, de Val N, Miller GM, Brown J, Schlossman A, Meng X, Crotty S, Peters B, Xiang Y, Hsieh-Wilson LC, Ward AB, Zajonc DM. Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E PLoS Pathog 2014 Dec;10(12):1004495-1004495. |
| Kaever T, Meng X, Matho MH, Schlossman A, Li S, Sela-Culang I, Ofran Y, Buller M, Crump RW, Parker S, Frazier A, Crotty S, Zajonc DM, Peters B, Xiang Y. Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein Journal of Virology 2014 Oct;88(19):11339-11355. |
| Meng X, Wu X, Yan B, Deng J, Xiang Y. Analysis of the role of vaccinia virus H7 in virion membrane biogenesis with an H7-deletion mutant J Virol 2013 Jul;87(14):8247-8253. |
| Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, Crotty S. Unusual features of vaccinia virus extracellular virion form (EV) neutralization resistance revealed in human antibody responses to the smallpox vaccine J Virol 2012 Nov;87(3):1569-1585. |
| Matho MH, Maybeno M, Benhnia MR, Becker D, Meng X, Xiang Y, Crotty S, Peters B, Zajonc DM. Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5 Journal of Virology 2012 Aug;86(15):8050-8058. |
| Wu X, Meng X*, Yan B, Rose L, Deng J and Xiang Y* (*corresponding author). Vaccinia virus virion membrane biogenesis protein A11 associates with viral membranes in a manner that requires the expression of another membrane biogenesis protein A6 Journal of Virology 2012 Aug;86(20):11276-11286. |
| Krumm B, Meng X, Wang Z, Xiang Y* and Deng J*(*corresponding authors). A Unique Bivalent Binding and Inhibition Mechanism by the Yatapoxvirus Interleukin 18 Binding Protein PLos Pathogens 2012 Aug;8(8). |
| Meng X, Schoggins J, Rose L, Cao J, Ploss A, Rice CM, Xiang Y. C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1 Journal of Virology 2012 Apr;86(8):4538-4547. |
| Meng X, Embry A, Rose L, Yan B, Xu C, Xiang Y. Vaccinia Virus A6 is Essential for Trafficking of Primary Virion Membrane Proteins to Sites of Virion Assembly Journal of Virology 2012 Mar;86(10):5603-5613. |
| Meng X, Xiang Y. Generation and characterization of monoclonal antibodies specific for vaccinia virus Methods Mol Biol 2012 Jan;890:219-232. |
| Xu C, Meng X*, Yan B, Crotty S, Deng J, and Xiang Y* (*corresponding author). An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies Virology 2011 Sep;418(1):67-73. |
| Embry A, Meng X, Cantwell A, Dube PH, Xiang Y. Enhancement of immune response to an antigen delivered by vaccinia virus by displaying the antigen on the surface of intracellular mature virion Vaccine 2011 Jun;29(33):5331-5339. |