Sathyaseelan, DeepaGraduate School of Biomedical Sciences |
| 11/2012 - Present | Assistant Professor/Research | University of Texas Health Science Cente at San Antonio, Cellular and Structural Biology, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 2010 | Postdoctoral Training | Type 2 diabetes/metabolic syndrome | University of Texas Health Science Center at San Antonio San Antonio , TX |
| 2006 | Postdoctoral Training | Neuronal plasticity | University of Cambridge Cambridge , United Kingdom |
| 2004 | Postdoctoral Training | Proteoglycan Biochemistry | Kobe Pharmaceutical University Kobe , Japan |
| 2000 | PhD | Biochemistry | University of Kerala Trivandrum , India |
| 1993 | MS | Biochemistry (First Rank) | University of Kerala Trivandrum , India |
| 1991 | BS | Chemistry (Distinction) | University of Kerala Trivandrum , India |
Type 2 diabetes, Mitochondria, Aging- Role of mitochondria in metabolic disorders and aging. |
Journal Article |
| Mizumoto S, Murakoshi S, Kalayanamitra K, Deepa SS, Fukui S, Kongtawelert P, Yamada S, Sugahara K. Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioctivities Glycobiology 2012 Sep;. |
| Deepa SS, Zhou, L, Ryu, J, Wang, C, Mao, X, Li, C, Zhang, N, Musi N, Zhang, BB, Liu F, Dong LQ. APPL1 Mediates Adiponectin-induced LKB1 Cytosolic Localization through the PP2A-PKCz Signalling Pathway Mol. Endocrinol 2011 Jan;25(10):1773-1785. |
| Carulli D, Pizzorusso T, Kwok JC, Putignano E, Poli A, Forostyak S, Andrews MR, Deepa SS, Glant TT, Fawcett JW. Animals lacking link protein have attenuated perineuronal nets and persistent plasticity Brain 2010 Aug;133:2331-2347. |
| Zhou L*, Deepa SS*, Etzler JC, Ryu J, Mao X, Fang Q, Liu DD, Torres JM, Jia W, Lechleiter JD, Liu F, Dong LQ. Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2 /Ca2 /calmodulin-dependent protein kinase kinase-dependent pathways (*Equal contribution) J Biol Chem 2009 Jan;284(33):22426-22435. |
| Deepa SS, Dong L, Sathyaseelan D. APPL1: role in adiponectin signaling and beyond Am J Physiol Endocrinol Metab 2009 Jan;296(1):22-36. |
| Pothacharoen P, Kalayanamitra K, Deepa SS, Fukui S, Hattori T, Fukushima N, Hardingham T, Kongtawelert P, Sugahara K. Two related but distinct chondroitin sulfate mimetope octasaccharide sequences recognized by monoclonal antibody WF6 J Biol Chem 2007 Nov;282(48):35232-35246. |
| Deepa SS, Yamada S, Fukui S, Sugahara K. Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes Glycobiology 2007 Jun;17(6):631-645. |
| Deepa SS, Kalayanamitra K, Ito Y, Kongtawelert P, Fukui S, Yamada S, Mikami T, Sugahara K. Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate E: sequencing and application for determination of the epitope structure of the monoclonal antibody MO-225 Biochemistry 2007 Mar;46(9):2453-2465. |
| Deepa SS, Carulli D, Galtrey C, Rhodes K, Fukuda J, Mikami T, Sugahara K, Fawcett JW. Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans J Biol Chem 2006 Jun;281(26):17789-17800. |
| Deepa SS, Yamada S, Zako M, Goldberger O, Sugahara K. Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control binding of J Biol Chem 2004 Sep;279(36):37368-37376. |
| Deepa SS, Arumughan C. Purification and characterization of soluble peroxidase from oil palm (Elaeis guineensis Jacq) leaf Phytochemistry 2002 Nov;61(5):503-511. |
| Deepa SS, Umehara Y, Higashiyama S, Itoh N, Sugahara K. Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner in the brain and other tissues J Biol Chem 2002 Nov;277(46):43707-43716. |
| Yamada S, Okada Y, Ueno M, Iwata S, Deepa SS, Nishimura S, Fujita M, Van Die I, Hirabayashi Y, Sugahara K. Determination of the glycosaminoglycan-protein linkage region oligosaccharide structures of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans J Biol Chem 2002 Aug;277(35):31877-31886. |
| Sivan YS, Alwin Jayakumar Y, Arumughan C, Sundaresan A, Jayalekshmy A, Suja KP, Soban Kumar DR, Deepa SS, Damodaran M, Soman CR, Raman Kutty V, Sankara Sarma P. Impact of vitamin A supplementation through different dosages of red palm oil and retinol palmitate on preschool children J Trop Pediatr 2002 Feb;48(1):24-28. |
| Sivan YS, Jayakumar YA, Arumughan C, Sundaresan A, Balachandran C, Job J, Deepa SS, Shihina SL, Damodaran M, Soman CR, Raman Kutty V, Sankara Sarma P. Impact of beta-carotene supplementation through red palm J Trop Pediatr 2001 Apr;47(2):67-72. |
| Alwin Jayakumar Y, Sivan YS, Arumughan C, Sundaresan A, Balachandran C, Joseph Job, Deepa SS, Shahina SL, Malathi Damodaran, Soman CR, Raman Kutty V, Sankara Sarma P. Consumption profile of preschool children supplemented with β-carotene through red palm oil in a rural community in tamilnadu The Indian Journal of Nutrition 2001 Jan;38:199-208. |
| Deepa SS, Arumughan C. Extraction and characterization of peroxidases from oil palm (Elaeis guineensis Jacq.) fruit and leaf Journal of Food Science and Technology 2001 Jan;38:200-206. |
| Deepa SS, Sobankumar DR and Arumughan C. Oil body composition from oil palm fruit mesocarp (Elaeis guineensis Jacq.) during fruit ripening The Journal of the Oil Technologists Association of India 2001 Jan;33:3-6. |
Federal |
|
| Funding Agency | American Heart Association (AHA) |
| Title | Beginning Grant-in-Aid |
| Status | Active |
| Period | 1/2013 - 12/2014 |
| Role | Principal Investigator |
| Grant Detail | Molecular mechanisms of mitochondrial stress modulated insulin sensitivity |