Abstract |
| Fujikawa, T., Castorena, C.M., Lee, S., and Elmquist, J.K. Steroidogenic factor-1 in the ventromedial hypothalamus is required for skeletal muscle adaptations after exercise training Snowbird, Utah, USA; 2015 May. (Keystone Symposia ? Neuronal Control of Metabolic Physiology and Diseases).
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| Fujikawa, T., Elmquist, J.K. Melanocortin 4 receptors are partially required for the leptin?s anti-diabetic actions in an insulin-independent manner? Kyoto, Japan; 2015 Jan. (Keystone Symposia ? Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies).
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| Fujikawa, T., Castorena, C.M., Lee, S., and Elmquist, J.K. Steroidogenic factor-1 in the ventromedial hypothalamus mediates beneficial effects of exercise training on metabolism Miami, Florida, USA; 2014 Aug. (? ACSM Conference on Integrative Physiology of Exercise).
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| Fujikawa, T., Choi, Y.H., Donato, J., Jr., Kohno, D., Lee, J., Battiprolu, P.K., Hill, J.H., Hill, J.A.E., C. F, , Kim, K.W., and Elmquist, J.K. PI3K signaling in the VMH regulates metabolism and heart function Vancouver, Canada; 2014 Jan. (Keystone Symposia -Challenges and Opportunities in Diabetes Research and Treatment).
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| Fujikawa, T., Vianna, C.R., Thorel, F., Herrera, P.L., Elmquist, J.K., Coppari, R. Leptin receptors in POMC neurons exert a permissive role in leptin?s anti-type 1 diabetes action Colorado, USA; 2013 Jan. (Keystone Symposia Diabetes -New Insights into Mechanism of Disease and its Treatment).
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Journal Article |
| Fujikawa, T., Castorena, C.M., Pearson, M., Kusminski, C.M., Ahmed, N., Battiprolu, P.K., Kim, K.W., Lee, S., Hill, J.A., Scherer, P.E., Holland, L.W., and Elmquist, K.J. SF-1 Expression in the Hypothalamus is Required for Beneficial Metabolic Effects of Exercise eLife 2016 Nov;.
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| Fujikawa, T. *, and Coppari, R. Living without insulin: the role of leptin signaling in the hypothalamus Front Neurosci 2015 Sep;.
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| Anderson, G.A., Ramadori, G., Ioris, M.R., Galie, M., Berglund, D.E., Coate, C. K., Fujikawa, T., Pucciarelli, S., Moreschini, B., Amici, A., Andreani, C., and Coppari, R. Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6 Molecular metabolism 2015 Apr;:846-856.
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| Asterholm, I.W., Rutkowski, J.M., Fujikawa, T., Cho, Y.R., Fukuda, M., Tao, C., Wang, Z.V., Gupta, R.K., Elmquist, J.K., and Scherer, P.E. Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice Diabetologia 2014 Jun;57:1209-1218.
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| Fujikawa, T. * and Coppari, R. Hypothalamic-mediated control of glucose balance in the presence and absence of insulin Aging 2014 Feb;6:92-97.
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| Williams, K.W., Liu, T., Kong, X., Fukuda, M., Deng, Y., Berglund, E.D., Deng, Z., Gao, Y., Liu, T., Sohn, J.-W., Jia, L., Fujikawa, T., Kohno, D., Sccotte, M., Lee, S., Lee, S., Sun, K., Chang, Y., Scherer, P.E., and Elmquist, J.K
. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis Cell metabolism 2014 Jan;20:471-482.
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| Choi, Y.H.*, Fujikawa, T.* (co-first author), Lee, J., Reuter, A., and Kim, K.W. Revisiting the Ventral Medial Nucleus of the Hypothalamus: The Roles of SF-1 Neurons in Energy Homeostasis Front Neurosci 2013 Aug;7.
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| Fujikawa, T., Berglund, E.D., Patel, V.R., Ramadori, G., Vianna, C.R., Vong, L., Thorel, F., Chera, S., Herrera, P.L., Lowell, B.B., Elmquist, J.K., Baldi, P., and Coppari, R. Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin Cell metabolism 2013 May;18:431-444.
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| Yamada, H., Iwaki, Y., Kitaoka, R., Fujitani, M., Shibakusa, T., Fujikawa, T., Matsumura, S., Fushiki, T., and Inoue, K. Blood lactate functions as a signal for enhancing fatty acid metabolism during exercise via TGF-beta in the brain J Nutr Sci Vitaminol 2012 Feb;58(2):88-85.
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| Ramadori, G., Fujikawa, T., Fukuda, M., Anderson, J., Morgan, D.A., Mostoslavsky, R., Stuart, R.C., Perello, M., Vianna, C.R., Nillni, E.A., Rahmouni, K., and Coppari, R. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity Cell metabolism 2011 Dec;12(1):78-87.
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| Ramadori, G., Fujikawa, T., Anderson, J., Berglund, E.D., Frazao, R., Michan, S., Vianna, C.R., Sinclair, D.A., Elias, C.F., and Coppari, R. SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance Cell metabolism 2011 Mar;14(3):301-312.
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| Miyaki, T., Fujikawa, T., Kitaoka, R., Hirano, N., Matsumura, S., Fushiki, T., and Inoue, K. Noradrenergic projections to the ventromedial hypothalamus regulate fat metabolism during endurance exercise Neuroscience 2011 Feb;190:239-250.
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| Fujikawa, T., Chuang, J.C., Sakata, I., Ramadori, G., Coppari, R. Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice Proc Natl Acad Sci U S A 2010 Jun;107(40):17391-17396.
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| Kitaoka, R., Fujikawa, T., Miyaki, T., Matsumura, S., Fushiki, T., and Inoue, K. Increased Noradrenergic Activity in the Ventromedial Hypothalamus during Treadmill Running in Rats J Nutr Sci Vitaminol 2010 May;56(3):185-190.
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| Fujikawa, T., Fujita, R., Iwaki, Y., Matsumura, S., Fushiki, T., Inoue, K. Inhibition of fatty acid oxidation activates transforming growth factor-beta in cerebrospinal fluid and decreases spontaneous motor activity Physiology 2010 Mar;101(3):370-375.
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| Ramadori, G., Gautron, L., Fujikawa, T., Vianna, C.R., Elmquist, J.K., and Coppari, R. Central administration of resveratrol improves diet-induced diabetes Endocrinology 2009 Dec;150(12):5326-5333.
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| Matsumura, S., Shibakusa, T., Fujikawa, T., Yamada, H., Matsumura, K., Inoue, K., and Fushiki, T. Intracisternal administration of transforming growth factor-beta evokes fever through the induction of cyclooxygenase-2 in brain endothelial cells American journal of physiology. Regulatory, integrative and comparative physiology 2008 Jan;294(1):R266-R275.
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| Fujikawa, T., Matsumura, S., Yamada, H., Inoue, K., and Fushiki, T. Transforming growth factor-beta in the brain enhances fat oxidation via noradrenergic neurons in the ventromedial and paraventricular hypothalamic nucleus Brain Res 2007 Jun;1173:92-101.
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| Matsumura, S., Shibakusa, T., Fujikawa, T., Yamada, H., Inoue, K., and Fushiki, T. Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity Neuroscience 2007 Mar;144(3):1133-1134.
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