Lynch, Jane LockwoodSchool of Medicine |
|
|
I am a Professor and the Interim Division Chief at the University of Texas Health Science Center at San Antonio. I have been active with medical student and resident teaching for almost 30 years in both academic and private practice settings. I enjoy mentoring and engaging medical students, residents and fellows in all aspects of pediatric endocrine and diabetes care and have an active portfolio of clinical research projects at the University of Texas Health Science Center. I developed and continue to serve as the Fellowship Program Director of the Pediatric Endocrinology fellowship which began in 2007. Our 2010 ACGME site visit led to a Program Director commendation and we now have had an extended accreditation cycles and a successful CLER visit with no citations. I have been involved with our Pediatric Scholarship Oversight program for many years. I served as the Director of the Children`s Center at the Texas Diabetes Institute from 2005 -2011 and now remain active with my clinics and our clinical research based at that site. I am active with the American Academy of Pediatrics, serving six years as an inaugural invited author and editor of the PREP Endocrinology Writing followed by election to the AAP Section of Endocrinology Executive Committee, of which I am now the re-elected Chair. I have consistently been recognized annually as a peer selected San Antonio Best Doctors for our subspecialty since 2009, Castle Connolly Regional Top Doctor annually since 2012, and was recognized by the Bexar County Medical Society for their Extraordinary Women in Medicine Leadership Award in 2018. I am the local Principal Investigator on the NIH sponsored TODAY, TODAY genetics and a multitude of ancillary and related sub studies with the TODAY2 study to investigate longitudinal Type 2 Diabetes treatment outcomes and co-morbidities in adolescent patients. My role has included steering committee work, leading writing groups and I have led the tracking and adjudication of diabetes related hypertension and renal disease occurring at all of the study sites. I am the local PI for the Pediatric Diabetes Consortium as well as several industry related clinical trials of medications to treat Type 2 Diabetes in Youth. I am currently one of two US physicians invited to serve on the Global Pediatric Type 2 Diabetes Expert Committee with several international manuscripts in progress regarding patterns of Type 2 Diabetes onset and progression in youth around the globe. |
|
| 9/2016 - Present | Interim Division Chief of Endocrinology | The University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| 3/2014 - Present | Consultant | Methodist Children's Hospital, San Antonio, TX |
| 9/2012 - Present | Professor | University of Texas Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| 9/2012 - Present | Co-Director | Children`s Clinic, Texas Diabetes Institute, University Hospital, San Antonio, TX |
| 1/2005 - Present | Medical Staff Member | University Health System, San Antonio, TX |
| 1/2005 - Present | Director and Pediatric Endocrine Fellowship Director | UT Health Science Center at San Antonio, Pediatrics, San Antonio, TX |
| Year | Degree | Discipline | Institution |
| 1990 | Clinical Fellowship | Pedi-Endocrine/Child Psychiatry Fellowship Award | Massachusetts General Hospital/ Harvard Medical School Boston , MA |
| 1989 | Clinical Fellowship | Genetics, Endocrinology and Metabolism | Oklahoma Health Sciences Center-Children's Hospital of Oklahoma Oklahoma City , OK |
| 1987 | Residency | Pediatric Residency | University of Texas-Southwest-Children`s Medical Center Dallas , TX |
| 1985 | Internship | Pediatric Internship | Washington University- St. Louis Children`s Hospital St. Louis , MO |
| 1984 | MD | Medicine | Wright State University School of Medicine Dayton , OH |
| 1980 | BS | Microbiology (Honors Division) | Indiana University Bloomington , IN |
Chronic Endocrine Disease in Children- Dr. Lynch had an additional year of fellowship training to better address the behavioral and emotional aspects of chronic disease with an understanding of the impact on the family unit which included the first year didactics and consult liaison experience in the Massachusetts General Hospital Child Psychiatry Linda Pollen Award Program. Her interest in approaching complex medical issues with a focus on the family has led to her involvement in the funded Project Support Research Project at both her Texas Diabetes Institute and Santa Rosa Children?s Hospital setting. She has consulted with Winston School of San Antonio and local school nurses to improve the diabetes management guidelines for children with special needs. |
Diabetes- Dr. Lynch has expertise with prediabetes, T1 and T2 diabetes in children and adolescents. She was an Investigator in the seminal Diabetes Control and Complications Trial early in her career. She is actively investigating and collaborating to find new approaches to preventing and treating both Type 1 and Type 2 diabetes. The current studies address immune intervention, beta cell preservation and randomized medication trials which improve insulin sensitivity while minimizing weight gain. These studies are funded by NIH, PDC, Trial Net and industry and are approved by the UTHSCSA IRB. She is an Independent Investigator in research regarding the use of continuous glucose monitoring to minimize both hyper and hypoglycemia events in children and adolescents. |
| Date | Description | Institution | # Students |
| 8/2013 - Present | Preceptor for UTHSCSA Family Practice Graduate Course | University of Texas Health Science Center at San Antonio | |
| Family Practice graduate nurse practitioner students | |||
| 7/2013 - Present | Pediatric Fellows & Residents (9:30-10:30) | UT-Health San Antonio | 12 students |
| 7/2013 - Present | Camp Lecture for Medical Staff | UT-Health San Antonio | 9 students |
| 8/2008 - Present | Clinical Preceptor | University of Texas Health Science Center at San Antonio | |
| Weekly Clinical Preceptor for the UTHSCSA Adult Endocrinology Fellowship (4 hours/week) | |||
| 8/2005 - Present | Rotation Student Supervision | UT Health San Antonio | |
| 5/2005 - Present | Rotation Student Supervision | UT Health San Antonio | |
| 3/2005 - Present | Pediatric Endocrinology | The University of Texas Health Science Center | |
| Outpatient clinical instruction and mentoring of UTHSCSA and rotating MS3 and MS4 medical students for two or four week rotations where they are taught about Disorders of Thyroid, adrenal, growth and carbohydrate metabolism. The course includes weekly conference, lectures, and journal reviews with an elective rotation to the Austin Newborn Screening Program that Dr. Lynch developed in 2008. The course also includes a one hour insulin pump lecture with assessments developed as a Quality Improvement Project in 2009 by Dr. Lynch and Dr Pankratz. Dr. Lynch has also agreed to individual arrangements for research months and has overseen additional students who have volunteered to join the division during the Diabetes Camp Week. | |||
| 1/2005 - Present | Case Management Instruction | UT Health Science Center at San Antonio | 4 students |
| Case management conference for all students and residents of all levels on pediatric endocrinology, Fridays | |||
| 1/2005 - Present | Rotation Student Supervision | UT Health San Antonio | |
Abstract |
| William Tamborlane, Peiyao Cheng, Robin Gal, Craig Kollman, Michelle Van Name, Jane Lynch, Bryce Nelson. T1D and T2D Youth in the Pediatric Diabetes Consortium (PDC) Registries: Comparing Clinical Characteristics and Glycemic Control. ADA 78th Scientific Session, Orlando, FL, JUN 22-26, 2018. Poster Presentation; 2018 May. (JCHR). |
| Amodei N, Lynch JL, Hale DE, Ievers-Landis, C.E., Yasuda, P., Walders-Abramson, N.W., Drews, K.L., Kaplan, J. Katz, L., Lavietes, S., Saletsky, R., Seidman, D. Longitudinal Correlates of Youth Health Risk Behaviors among Children and Adolescents with Type 2 Diabetes in the TODAY Study; 2013 Jul. (Diabetes; vol. 62, no. Sup.). |
| Farook VS, Reddivari L, Chittoor G, Puppala S, Arya R, Fowler SP, Hunt KJ, Curran JE, Comuzzie A, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala J. Metabolites as Novel Biomarkers for Childhood Obesity-Related Traits in Mexican American Children; 2013 Jul. (American Diabetes Association, 73rd Scientific Sessions June 21-25, 2013; Chicago, IL; vol. 62, no. Sup1A). |
| Lynch JL, Willey-Courand DB, Rayas MS, Guajardo JR. Screening for Cystic Fibrosis-Related Diabetes by an Integrated Care Team Using an Algorithm; 2011 Jan. (Pediatric Pulmonology). |
Editorial |
| Lynch JL. Victoza: New Treatment Option for Youth with Type 2 Diabetes Interview July 8, 2019 for OnTrack Diabetes on line journal https://www.ontrackdiabetes.com/live-well/diabetes-management/victoza-new-treatment-option-youth-type-2-diabetes 2019 Jul;. |
| Lynch JL. May 2019: Express News Interview: https://www.expressnews.com/news/local/article/A-scary-disease-Children-with-Type-2-14059256.php 2019 May;. |
| Lynch JL. April 2019: Mission Magazine https://magazines.uthscsa.edu/mission/the-perfect-storm/ 2019 Apr;. |
| Lynch JL. City Issues: Health San Antonio Magazine 2017 May;. |
Journal Article |
| Bacha F, El Ghormli L, Arslanian S, Zeitler P4Laffel LM, Levitt Katz LE, Gandica R, Chang NT, Sprague JE, Macleish SA; TODAY Study Group. Jane L. Lynch. Predictors of response to insulin therapy in youth with poorly-controlled type 2 diabetes in the TODAY trial Pediatr Diabetes 2019 Nov;20(7):871-879. |
| Bjornstad P, Hughan K, Kelsey MM, Shah AS, Lynch J, Nehus E, Mitsnefes M, Jenkins T, Xu P, Xie C, Inge T, Nadeau K. Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes Diabetes Care [epub ahead of print} 2019 Nov;. |
| Songer TJ, Haymond MW, Glazner JE, Klingensmith GJ, Laffel LM, Zhang P, Hirst K; TODAY Study Group. Lynch JL. Healthcare and associated costs related to type 2 diabetes in youth and adolescence: the TODAY clinical trial experience Pediatr Diabetes 2019 Sep;20(6):702-711. |
| Grimes A, Mohamed A, Sopfe J, Hill R, Lynch JL. Hyperglycemia During Childhood Cancer Therapy: Incidence, Implications, and Impact on Outcomes J Natl Cancer Inst. Monogr 2019 Sep;2019(54):132-138. |
| Ruban Dhaliwal, John A. Shepherd, Laure E ghormli, Kenneth C. Copeland, Mitchell E. Geffner, Janine Higgins, Lynne L. Levitsky, Kristen J. Nadeau, Ruth S. Weinstock and Neil H. White, for the TODAY Study Group. Changes in Visceral and Subcutaneous Fat in Youth With Type 2 Diabetes in the TODAY Study Diabetes Care 2019 Aug;42(8):1549-1559. |
| Jalaludin MY, Barrientos-Perez M, Hafez M, Lynch J, Shehadeh N, Turan S, Weghuber D. Recommendations for improving clinical trial design to facilitate the study of youth-onset type 2 diabetes Clin Trials 2019 Aug;. |
| Petter Bjornstad, Lori Laffel, Jane Lynch, Laure El ghormli,Ruth S. Weinstock, Sherida E. Tollefsen, Kristen J. Nadeau, for the TODAY Study Group*. Elevated Serum Uric Acid Is Associated With Greater Risk for Hypertension and Diabetic Kidney Diseases in Obese Adolescents With Type 2 Diabetes: An Observational Analysis From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) St Diabetes Care 2019 Jun;42(6):1120-1128. |
| Weinstock RS, Braffett BH, McGuigan P, Larkin ME4, Grover NB, Walders-Abramson N, Laffel LM, Chan CL, Chang N, Schwartzman BE, Barajas RA, Celona-Jacobs N, Haymond MW; TODAY Study Group. Lynch JL. Self-Monitoring of Blood Glucose in Youth-Onset Type 2 Diabetes: Results From the TODAY Study Diabetes Care 2019 May;42(5):903-909. |
| Tamborlane WV, Barrientos-Perez M, Fainberg U, Frimer-Larsen H, Hafez M, Hale PM, Jalaludin MY, Kovarenko M, Libman I, Lynch JL, Rao P, Shehadeh N, Turan S, Weghuber D, Barrett T; Ellipse Trial Investigators. Liraglutide in Children and Adolescents with Type 2 Diabetes N Engl J Med 2019 Apr;. |
| Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH; TODAY Study Group. Lynch JL. The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in β-Cell Function in TODAY Diabetes Care 2019 Jan;42(1):164-172. |
| Tamborlane WV, Chang P, Kollman C, Klingensmith GJ, Ruedy K, Gal RL, Van Name M, Bacha F, Willi S, Beck RW; Pediatric Diabetes Consortium. Lynch JL. Eligibility for clinical trials is limited for youth with type 2 diabetes: Insights from the Pediatric Diabetes Consortium T2D Clinic Registry Pediatr Diabetes 2018 Dec;19(8):1379-1384. |
| Klingensmith GJ, Lanzinger S, Tamborlane WV, Hofer S, Cheng P, deBeaufort C, Gal RL, Reinehr T, Kollman C, Holl R. PDC Consortium: Lynch JL, Orsi CM, Rayas MS, Barajas R. Adolescent Type 2 Diabetes: Comparing the Pediatric Diabetes Consortium and Germany/Austria/Luxemburg Pediatric Diabetes Prospective Registries Pediatr Diabetes 2018 Nov;19(7):1156-1163. |
| Leena Nahata, Gwendolyn P. Quinn, Amy C. Tishelman. Section on Endocrinology Executive Committee, 2017?2018: Jane L. Lynch, MD, FAAP, Chairperson; Jill L. Brodsky, MD, FAAP; Samuel J. Casella, MD, MSc, FAAP; Linda A. DiMeglio, MD, MPH, FAAP; Ximena Lopez, MD, FAAP; Kupper A. Wintergerst, MD, FAAP; Irene Sills, MD, FAAP, Immediate Past Chairperson. Counseling in Pediatric Populations at Risk for Infertility and/or Sexual Function Concerns Pediatrics 2018 Aug;142(2). |
| Shah AS, El Ghormli L, Gidding SS, Bacha F, Nadeau KJ, Levitt Katz LE, Tryggestad JB, Leibel N, Hale DE, Urbina EM. TODAY TODAY2 STUDY GROUP: Lynch JL, Barajas R, Orsi, C and Wauters, A. Prevalence of arterial stiffness in adolescents with type 2 diabetes in the TODAY cohort: Relationships to glycemic control and other risk factors J Diabetes Complications 2018 Aug;32(8):740-745. |
| Selvakumar PKC, Kabbany MN, Lopez R, Rayas MS, Lynch JL, Alkhouri N. Prevalence of Suspected Nonalcoholic Fatty Liver Disease In Lean Adolescents In The United States J Pediatr Gastroenterol Nutr 2018 Jul;67(1):75-79. |
| Nathan E. McWhorter, Leen Abazid, Brandon C. Gorzell, Jane L. Lynch, Umber A. Salman, Darlene F. Metter and William T. Phillips. Simultaneous blood glucose monitoring during gastric emptying scintigraphy may identify unsuspected abnormalities Clinical Nuclear Medicine 2018 Jun;43(6):411-419. |
| Kelsey MM, Braffett BH, Geffner ME, Levitsky LL, Caprio S, McKay SV, Shah R, Sprague JE, Arslanian SA; TODAY Study Group. Lynch JL. Menstrual Dysfunction in Girls From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study J Clin Endocrinol Metab 2018 Jun;103(6):2309-2318. |
| Arya R, Farook VS , Fowler SP, Puppala S, Chittoor G, Resendez RG, Mummidi S, Vanamala J , Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R,. Diego VP. Genetic and Environmental (Physical Fitness and Sedentary Activity) Interaction Effects on Cardiometabolic Risk Factors in Mexican American Children and Adolescents Genetic Epidemiology 2018 Jun;42(4):378-393. |
| Levitt Katz LE, Bacha F, Gidding SS, Weinstock RS, El Ghormli L, Libman I, Nadeau KJ, Porter K, Marcovina S; TODAY Study Group. Lynch, JL; Hale DE. Lipid Profiles, Inflammatory Markers, and Insulin Therapy in Youth with Type 2 Diabetes J Pediatr 2018 May;196:208-216. |
| Gidding SS, Bacha F, Bjornstad P, Levitt Katz LE, Levitsky LL, Lynch J, Tryggestad JB, Weinstock RS, El Ghormli L, Lima JAC; TODAY Study Group. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study J Pediatr 2018 Jan;192:86-92 e5. |
| Bacha F, Cheng P, Gal RL, Kollman C, Tamborlane WV, Klingensmith GJ, Manseau K, Wood J, Beck RW; for the Pediatric Diabetes Consortium. Lynch JL. Initial Presentation of Type 2 Diabetes in Adolescents Predicts Durability of Successful Treatment with Metformin Monotherapy: Insights from the Pediatric Diabetes Consortium T2D Registry Horm Res Paediatr 2018 Jan;18(1):47-55. |
| Bjornstad P, Nehus E, El Ghormli L, Bacha F, Libman IM, McKay S, Willi SM, Laffel L, Arslanian S, Nadeau KJ; TODAY Study Group. (Lynch, J; Hale, D). Insulin Sensitivity and Diabetic Kidney Disease in Children and Adolescents With Type 2 Diabetes: An Observational Analysis of Data From the TODAY Clinical Trial Am J Kidney Dis 2018 Jan;71(1):65-74. |
| Purnell JQ, Braffett BH, Zinman B, Gubitosi-Klug RA, Sivitz W, Bantle JP, Ziegler G, Cleary PA, Brunzell JD; DCCT/EDIC Research Group. Lynch, J. Impact of Excessive Weight Gain on Cardiovascular Outcomes in Type 1 Diabetes: Results From the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Diabetes Care 2017 Dec;40(12):1756-1762. |
| Hutchins J, Barajas RA, Hale DE, Escaname EN, Lynch JL. Type 2 diabetes in a 5 year old and single center experience of Type 2 diabetes in youth under 10 Pediatric Diabetes 2017 Nov;18(7):674-677. |
| Magge SN, Goodman E, Armstrong SC; COMMITTEE ON NUTRITION; SECTION ON ENDOCRINOLOGY; SECTION ON OBESITY. The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering Pediatrics 2017 Aug;140(2):e1-e14. |
| Marcus MD, Wilfley DE, El Ghormli L, Zeitler P, Linder B, Hirst K, Ievers-Landis CE, van Buren DJ, Walders-Abramson N; TODAY Study Group. Weight change in the management of youth-onset type 2 diabetes: the TODAY clinical trial experience Pediatr Obes 2017 Aug;12(4):337-345. |
| Farook VS, Reddivari L, Mummidi S, Puppala S, Arya R, Lopez-Alvarenga JC, Fowler SP, Chittoor G, Resendez RG, Kumar BM, Comuzzie AG, Curran JE, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala JK . Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children Am J Clin Nutr 2017 Jul;106(1):52-58. |
| Berkowitz RI, Marcus MD, Anderson BJ, Delahanty L, Grover N, Kriska A, Laffel L, Syme A, Venditti E, Van Buren DJ, Wilfley DE, Yasuda P, Hirst K; TODAY Study Group. Adherence to a lifestyle program for youth with type 2 diabetes and its association with treatment outcome in the TODAY clinical trial Pediatr Diabetes 2017 Jun;. |
| Lynch JL; DCCT/EDIC Research Group, Nathan DM, Bebu I, Hainsworth D, Klein R, Tamborlane W, Lorenzi G, Gubitosi-Klug R, Lachin JM. Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes N Engl J Med 2017 Apr;376(16):1507-1516. |
| Kriska A, El Ghormli L, Copeland KC, Higgins J, Ievers-Landis CE, Levitt Katz LE, Trief PM, Wauters AD, Yasuda PM, Delahanty LM1; TODAY Study Group.(Lynch, JL). Impact of lifestyle behavior change on glycemic control in youth with type 2 diabetes Pediatr Diabetes 2017 Apr;. |
| Bonny Rockette-Wagner; Kristi L. Storti; Sharon Edelstein; Linda M. Delahanty; Bryan Galvin; Alexandra Jackson and Andrea M. Kriska (Today Study: Jane L. Lynch). Measuring Physical Activity and Sedentary Behavior in Youth with Type 2 Diabetes Child Obes 2017 Feb;13(1):72-77. |
| Arslanian S, El Ghormli L, Bacha F, Caprio S, Goland R, Haymond MW, Levitsky L, Nadeau KJ, White NH, Willi SM; TODAY Study Group.(Lynch, JL). Adiponectin, Insulin Sensitivity, β-Cell Function, and Racial/Ethnic Disparity in Treatment Failure Rates in TODAY Diabetes Care 2017 Jan;40(1):85-93. |
| Katz LL, Anderson BJ, McKay SV, Izquierdo R, Casey TL, Higgins LA, Wauters A, Hirst K, Nadeau KJ; TODAY Study Group. Correlates of Medication Adherence in the TODAY Cohort of Youth with Type 2 Diabetes Diabetes Care 2016 Nov;39(11):1956-1962. |
| Lenherr SM, Clemens JQ, Braffett BH, Cleary PA, Dunn RL, Hotaling JM, Jacobson AM, Kim C, Herman W, Brown JS, Wessells H, Sarma AV; DCCT/EDIC Research Group. Lynch JL. Glycemic Control and Urinary Tract Infections in Women with Type 1 Diabetes: Results from the DCCT/EDIC J Urol 2016 Oct;196(4):1129-1135. |
| Bachrach LK, Gordon CM; SECTION ON ENDOCRINOLOGY. Bone Densitometry in Children and Adolescents Pediatrics 2016 Oct;138(4). |
| Nadeau KJ, Anderson BJ, Berg EG, Chiang JL, Chou H, Copeland KC, Hannon TS, Huang TT, Lynch JL, Powell J, Sellers E, Tamborlane WV, Zeitler P. Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities Diabetes Care 2016 Sep;39(9):1635-1642. |
| Chen Z, Miao F, Paterson AD, Lachin JM, Zhang L, Schones DE, Wu X, Wang J, Tompkins JD, Genuth S, Braffett BH, Riggs AD; DCCT/EDIC Research Group, Natarajan R. Lynch JL. Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort Proc Natl Acad Sci U S A 2016 May;113(21):E3002-E3011. |
| Tamboralane WV; Haymond MW; Dunger D; Shankar R; Gubitosi-Klug R; Bethin K; Karres J; Tomasi P; Libman I; Hale PH; Portman R; Klingensmith G; Reed M; Blumer J; Giacoia G; NICHD Diabetes Working Group: Lynch JL; Chilton RJ. Expanding Treatment Options for Youth With Type 2 Diabetes: Current Problems and Proposed Solutions: A White Paper From the NICHD Diabetes Working Group Diabetes Care 2016 Mar;39(3):323-329. |
| Klingensmith GJ1, Pyle L2, Nadeau KJ3, Barbour LA4, Goland RS5, Willi SM6, Linder B7, White NH8; TODAY Study Group. (Lynch, JL). Pregnancy Outcomes in Youth With Type 2 Diabetes: The TODAY Study Experience Diabetes Care 2016 Jan;39(1):122-129. |
| Kaplowitz P, Bloch C; Section on Endocrinology, American Academy of Pediatrics. Evaluation and Referral of Children With Signs of Early Puberty Pediatrics 2016 Jan;137(1). |
| Zeitler P, Hirst K, Copeland KC,El Ghormli L, Levitt Katz L, Levitsky LL, Linder B, McGuigan P, White NH, Wilfley D,TODAY STUDY GROUP* Lynch JL. HbA1c After a Short Period of Monotherapy With Metformin Identifies Durable Glycemic Control Among Adolescents With Type 2 Diabetes Diabetes Care 2015 Dec;38(12):2285-2292. |
| Eny KM, Orchard TJ, Miller RG, Maynard J, Grant DM, Costacou T, Cleary PA, Braffett BH, Paterson AD; DCCT/EDIC Research Group. Lynch JL. Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes Diabetes Technol Ther 2015 Oct;17(10):726-734. |
| Farook VS, Reddivari L, Chittoor G, Puppala S, Arya R, Fowler SP, Hunt KJ, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala J. Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children Pediatr Obes 2015 Aug;10(4):320-327. |
| Ievers-Landis CE, Walders-Abramson N, Amodei N, Drews KL, Kaplan J, Levitt Katz LE, Lavietes S, Saletsky R, Seidman D, Yasuda P;Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study Group: Lynch JL; Hale DE; Orsi CM; Rayas M. Longitudinal Correlates of Health Risk Behaviors in Children and Adolescents with Type 2 Diabetes J Pediatr 2015 May;166(5):1258-1264. |
| Weinstock RS, Trief PM, El Ghormli L, Goland R, McKay S, Milaszewski K, Preske J, Willi S, Yasuda PM. [TODAY-Jane L Lynch]. Parental Characteristics Associated With Outcomes in Youth With Type 2 Diabetes: Results From the TODAY Clinical Trial Diabetes Care 2015 May;38(5):784-792. |
| DCCT/EDIC Research Group, Aiello LP, Sun W, Das A, Gangaputra S, Kiss S, Klein R, Cleary PA, Lachin JM, Nathan DM. Lynch JL. Intensive diabetes therapy and ocular surgery in type 1 diabetes N Engl J Med 2015 Apr;372(18):1722-1733. |
| Levitt Katz L, Gidding SS, Bacha F, Hirst K, McKay S, Pyle L, Lima JA; TODAY Study Group.Lynch JL, Hale DE. Alterations in left ventricular, left atrial, and right ventricular structure and function to cardiovascular risk factors in adolescents with type 2 diabetes participating in the TODAY clinical trial Pediatr Diabetes 2015 Feb;16(1):39-47. |
| Rayas MS, Willey-Courand DB, Lynch JL, Guajardo JR. Improved Screening for Cystic Fibrosis-Related Diabetes by an Integrated Care Team Using an Algorithm Pediatric Pulmonology 2014 Oct;49(10):971-977. |
| Walders-Abramson N, Venditti EM, Ievers-Landis CE, Anderson B, El Ghormli L, Geffner M, Kaplan J, Koontz MB, Saletsky R, Payan M, Yasuda P; Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study Group. Lynch JL, Cody JD, Hale DE. Relationships among stressful life events and physiological markers, treatment adherence, and psychosocial functioning among youth with type 2 diabetes J Pediatr 2014 Sep;165(3):504-508. |
| TODAY Study Group:Lynch JL, Hale DE. Effects of metformin, metformin plus rosiglitazone, and metform plus lifestyle on insulin sensitivity and β-cell function in TODAY Diabetes Care 2013 Jun;36(6):1749-1757. |
| TODAY Study Group, Zeitler P, Hirst K, Pyle L, Linder B, Copeland K, Arslanian S, Cutter L, Nathan DM, Tollefsen S, Wilfley D, Kaufman F. A clinical trial to maintain glycemic control in youth with type 2 diabetes N Engl J Med 2012 Jun;366(24):2247-2256. |
| TODAY Study Group, Wilfey D, Berkowitz R, Goebel-Fabbri A, Hirst K, levers-Landis C, Lipman TH, Marcus M, Ng D, Pham T, Saletsky R, Schanuel J, Van Buren D. Binge eating, mood, and quality of life in youth with type 2 diabetes: baseline data from the TODAY study Diabetes Care 2011 Apr;34(4):858-860. |
| Orsi CM, Hale DE, Lynch JL. Pediatric obesity epidemiology Curr Opin Endocrinol Diabetes Obes 2011 Feb;18(1):14-22. |
| TODAY Study Group, Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffal L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B. TODAY Study Group. The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY Study Diabetes Care 2010 Sep;33(9):1970-1975. |
| TODAY Study Group. TODAY Study Group. Design of a family-based lifestyle intervention for youth with type 2 diabetes: the TODAY Study Int J Obes (Lond) 2010 Feb;34(2):217-226. |
Review Article |
| Solis-Herrera C, Triplett CL, Lynch JL. Nephropathy in youth and young adults with type 2 diabetes Current Diabetes Reports 2014 Feb;14(2). |
Federal |
|
| Funding Agency | George Washington University - NIH Flow Through |
| Title | TODAY 2 Phase 2 (T2P2): Long-Term Post Intervention Follow Up |
| Status | Active |
| Period | 5/2016 - 4/2020 |
| Role | Principal Investigator |
| Grant Detail | Follow Up Study of T2 Diabetes Children who have completed the TODAY Study with medical therapy and annual studies. TODAY study data is currently being analyzed. This study will then be further extended by final design which is under development and incorporating preliminary TODAY outcome data. This is a 5 year continuation for the long-term evaluation of the cohort that completed the TODAY2 Phase 1 component. |
| Funding Agency | University of South Florida |
| Title | Type 1 Diabetes TrialNet - Major Affiliates |
| Status | Complete |
| Period | 9/2008 - 6/2019 |
| Role | Co-Investigator |
| Grant Detail | (PGID# 128288) Cost recoverable contract. |
Private |
|
| Funding Agency | Jaeb Center for Health Research |
| Title | Pediatric Diabetes Consortium Type 2 Diabetes Registry |
| Status | Active |
| Period | 7/2015 - 12/2019 |
| Role | Principal Investigator |
| Grant Detail | This is a joint collaboration between Jaeb Center for Health Research (JCHR) and The University of Texas Health Science Center to generate a registry of Type 2 diabetes patients. This registry will gather pertinent information on the patients in order to follow up on comprehensive care as it relates to their diabetic issues. This registry will create a cohort of Type 2 patients that will be helpful for other research-related projects. Income will be derived from a cost-reimbursable mechanism. |